1. E


    Hallo guys, :-) I have already seen that in this forum the following synthesis route is discussed: "New and mild method for the synthesis of alprazolam..." Synthesis of 7-chloro-5-phenyl-1H benzo[e][1,4]diazepin-2(3H)-one (nordiazepam) (Step 1) To a vigorously stirred of 2-amino-5-chloro...
  2. B

    Imidazenil CAS151271-08-8

    Hey guys, I want to bring to attention a compound that is literally capable of helping the suffering of so many who are trying to weane down from benzos or suffer anxiety. Someone should really just on the bandwagon and synth this, the ingredients aren't cheap but the demand would be...
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  4. Agilent1100DAD

    Polymorphism of Alprazolam (Xanax) and Its Relation to Possible Polymorphs of Intermediate, Nordiazepam. Publication Review and In-House Experiment

    I have uploaded a PDF of the publication, the purpose of this post is to review some key information that pertains to the clandestine chemist in the field of benzo synthesis. I conducted a series of experiments today which involved the recrystilization of nordiazepam in methanol & ethanol. I...
  5. M

    Questions regarding alprazolam/flualprazolam synthesis

    My reference material is 10.1007/s00044-016-1585-z and the small scale alprazolam synthesis that I found here - I do understand the basic process. I do have a few questions though, and can't really find answers to them online elsewhere. The precursor of 2-amino-5-chlorobenzophenone is for...
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