Introduction
(-)-Cocaine is a naturally derived alkaloid obtained from coca leaves. In contrast, racemic cocaine and its (+)-enantiomer can only be synthesized chemically. This article outlines a streamlined total synthesis method for both the single enantiomers of cocaine and racemic cocaine...
Reagents Needed:
Kerosene,
Solid Na2CO3,
Distilled H2O,
H2SO4 5%
Solid KMnO4 (6% Solution is used) NH4OH 10%,
HCl 37%,
Acetone,
Diethyl Ether.
Note: The pictures were taken from 2 extractions performed with ~2 Kg and ~5 Kg of leaves, but all the procedure outlined refers to the...