leuckart

  1. J

    there seems to be a debate about the quality of the meth through nabh4

    Question 
    i know that nabh4 method is the most preferred one due to its scalability, but quality wise, some say nabh4 meth has weaker effect and effect time even after separation of the racemic into d - isomer as far as i know, from p2p, there are al/hg, nabh4, leuckart anyone tried each synth? which...
  2. K

    Difference in Leuckart Reaction with Formamide and ammonium formate

    Hello Guys, At First I want to say what a nice forum this is! really interesting! I have a question about the Leuckart reaction to produce amphetamines and maybe someone here can help me: The literature speaks of two different methods for the Leuckart reaction: one with ammonium formate and one...
  3. S

    Amphetamine via leuckart reaction?

    Hello I tried to do a search on the forum for the leuckart reaction for amphetamine but i could only find it for methamphetamine. Does anyone on here know that particular route towards amphetamine and could possibly post it on the forum? thanks
  4. William D.

    1-Phenyl-2-propanone (P2P) Leuckart amination to amphetamine and methamphetamine. Smale scale.

    Amphetamine Reagents: 1-Phenyl-2-propanone (P2P) 0.827 g, 6.2 mmol; Formamide 3.5 ml; Benzene 50 ml; Magnesium sulphate (MgSO4); Methanol 5 ml (MeOH); Hydrochloric acid (15 % aq HCl) 5 ml; Distilled water 25 ml; Dichloromethane (DCM) 90 ml; Sodium hydroxide (NaOH) pellets; Sulfuric acid...
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