leuckart

  1. K

    Difference in Leuckart Reaction with Formamide and ammonium formate

    Hello Guys, At First I want to say what a nice forum this is! really interesting! I have a question about the Leuckart reaction to produce amphetamines and maybe someone here can help me: The literature speaks of two different methods for the Leuckart reaction: one with ammonium formate and one...
  2. S

    Amphetamine via leuckart reaction?

    Hello I tried to do a search on the forum for the leuckart reaction for amphetamine but i could only find it for methamphetamine. Does anyone on here know that particular route towards amphetamine and could possibly post it on the forum? thanks
  3. William Dampier

    1-Phenyl-2-propanone (P2P) Leuckart amination to amphetamine and methamphetamine. Smale scale.

    Amphetamine Reagents: 1-Phenyl-2-propanone (P2P) 0.827 g, 6.2 mmol; Formamide 3.5 ml; Hydrogen peroxide (H2O2) 5 ml 30%; Benzene 50 ml; Magnesium sulphate (MgSO4); Methanol 5 ml (MeOH); Hydrochloric acid (15 % aq HCl) 5 ml; Distilled water 25 ml; Dichloromethane (DCM) 90 ml; Sodium hydroxide...
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