Cocaine Synthesis from Tropinone

[Frit Buchner]

The CHINESE will sell you 2-cmt, which is only a couple Reactions away. I got a price quote from them but I couldn't afford it based on my fear that I couldn't pull it off. They quoted me $150 for a 10g sample. So you are probably looking at...idk, $10,000 kg?
I know it works because about 1 out of 200 samples tested by drugs-data, where you mail it in and pay $100, is synthetic cocaine.

2-Carbomethoxytropinone - Wikipedia

en.m.wikipedia.org

 

[Germanium]

The CHINESE will sell you 2-cmt, which is only a couple Reactions away. I got a price quote from them but I couldn't afford it based on my fear that I couldn't pull it off. They quoted me $150 for a 10g sample. So you are probably looking at...idk, $10,000 kg?
I know it works because about 1 out of 200 samples tested by drugs-data, where you mail it in and pay $100, is synthetic cocaine.

2-Carbomethoxytropinone - Wikipedia

en.m.wikipedia.org

Frit BuchnerIf I want to synthesize from 2 cmt, what is the procedure?
Any examples would be helpful...

 

[Frit Buchner]

If I want to synthesize from 2 cmt, what is the procedure?
Any examples would be helpful...

GermaniumI wrote about it, either above or in another thread about this topic. An alkylation reaction (methylation) and a Fischer esterfication are the 2 reactions. You can find examples in pretty much every cocaine synthesis scheme. I wouldn't suggest one over another based on I haven't done it.

 

[Germanium]

I wrote about it, either above or in another thread about this topic. An alkylation reaction (methylation) and a Fischer esterfication are the 2 reactions. You can find examples in pretty much every cocaine synthesis scheme. I wouldn't suggest one over another based on I haven't done it.

Frit BuchnerOkay. Thanks!
I will search more and read past posts.

 

[OmID]

Hi everyone
I'm going to synthesis cocaine from tropinone and I will share the pictures and videos on this site.
I'm a bit noob and this is my second synthesize.
I have few questions:
1; tropinone is not solves in ether but how received unredacted tropinone of it?
2; turn 2 cmt into ecgonine
At first I'm have in mind use nagh amalgam but it's sund nabh is way easier
But I can't find any data on internet
3; I make nagh amalgam and have no idea for Purification of it
4; at the end how to split racemic cocaine and cocaine
At the end I'm apologize for my poor English knowledge and any help even a Link or short sentence could be useful

 

[Frit Buchner]

I can link you to the documents that answer these questions but I can't elaborate on them. This is a lofty goal for a second synthesis. I've read that the enantiomers of cocaine also have some cns activity so I'm not sure that you have to seperate them.

 

[OmID]

I can link you to the documents that answer these questions but I can't elaborate on them. This is a lofty goal for a second synthesis. I've read that the enantiomers of cocaine also have some cns activity so I'm not sure that you have to seperate them.

Frit BuchnerBy doing this, you are doing me a great favor

 

[OmID]

i added 3.48 g tropinone 1.38 g nametoxid in to a fbf 50 ml flask and pur a mixture containing a 4ml dimethyl carbonat and 10ml toluene.
Now I'm waiting for any color change

 

[The-Hive]

Any update on this

 

[OmID]

After reflux I bring the temperature to 0
Ad 2.5 g nhcl4 15 ml water mixture extract whit chloroform (50) ml and put into Separatory funnel and wash the rbf whit chloroform 50 ml
Al solvents mix to separatory funnel shake 3 times 3m
And extract 2 times more whit 50 ml
And I extract 2 times more for better results
I get a cloudy solution and dried
Now I'm going to vacuum distillate chloroform

 

[9-Tryptophan]

After reflux I bring the temperature to 0
Ad 2.5 g nhcl4 15 ml water mixture extract whit chloroform (50) ml and put into Separatory funnel and wash the rbf whit chloroform 50 ml
Al solvents mix to separatory funnel shake 3 times 3m
And extract 2 times more whit 50 ml
And I extract 2 times more for better results
I get a cloudy solution and dried
Now I'm going to vacuum distillate chloroform
View attachment 35133

OmIDDid you get something out after vacuum Destillation?

 

[OmID]

Did you get something out after vacuum Destillation?

9-TryptophanYes I get a yellow to Brown oil
And at the end
This synthesis was not interesting to the members, so I stopped posting the steps to the forum

 

[The-Hive]

Looks so simple but we all know it’s not. They are several discussions on this synthesis on the forum. someone was saying you’ll be lucky to get 5%.

 

[OmID]

Looks so simple but we all know it’s not. They are several discussions on this synthesis on the forum. someone was saying you’ll be lucky to get 5%.

The-HiveMy motivation in this synthesis is not money, dear friend I can access the product at half the price of tropinone If I reach even 1%, it is a victory for me If I don't get any results, at least I enjoyed the journey

 

[The-Hive]

I wasn’t being negative towards what you were doing . It would be amazing to see this synthesis