Discussion: Alcohol and Tramadol

[HEISENBERG]

Alcohol and Tramadol​

When a person consumes alcohol, it goes to the brain where it affects the function of certain neurotransmitters, including GABA and glutamate. These neurotransmitters play a role in regulating mood, behavior, and other cognitive functions. Alcohol increases the activity of GABA, which can lead to feelings of relaxation and pleasure. It also reduces the activity of glutamate, which can cause impairments in cognitive function, such as memory loss, difficulty thinking clearly, and slowed reaction time.

Tramadol is a prescription pain medication that is used mostly to treat moderate to severe pain. When tramadol is taken orally, it is absorbed into the bloodstream through the digestive tract. From there, it is carried to the brain where it binds to opioid receptors. Tramadol can also inhibit the reuptake of serotonin and norepinephrine, which are neurotransmitters involved in pain perception, among other things. Common side effects of tramadol include dizziness, drowsiness, nausea, and constipation. More severe side effects can include respiratory depression.

The combination of Tramadol and Alcohol can be dangerous because both substances are depressants, which means they slow down the activity of the brain. When taken together, the combination can increase the risk of drowsiness, respiratory depression, coma, and other and other side effects associated with central nervous system depression.

Among the side effects characteristic of the combination of alcohol and Tramadol, one can also highlight:

• Increased intracranial pressure and recurring episodes of headache.
• Frequent nausea, vomiting, and abdominal pain.
• More likely to cause liver damage than when using these substances alone.
• Impaired kidney function up to renal failure

Alcohol also can enhance the effects of Tramadol on the body and increase the risk of overdose and other serious side effects. For example, alcohol can increase the risk of liver damage, which in the case of isolated use of Tramadol is a consequence of long-term exposure.

There are cases of severe convulsive seizures when Tramadol is used in combination with one or another substance. In the case of Alcohol, this is most likely due to impaired liver function and the multi-vector activity of Tramadol on neurotransmitters. While Alcohol and Tramadol have different touchpoints, they may be synergistic in lowering the seizure threshold.

Finally, various studies show that the simultaneous use of Alcohol and Tramadol increases the potential for substance abuse and is directly associated with higher mortality.

All things considered, we recommend avoiding this combination.

 

[endingcart]

I have tried with 400mg of tramadol, 6 beers and two shots of vodka. The first two beers I felt the effects of alcohol and tramadol simultaneously, after the fourth beer it was just the alcohol, tramadol effects completely disappeared. I guess if you don't drink a lot is not that dangerous but it depends on how much you drink.

 

[Paracelsus]

I have tried with 400mg of tramadol, 6 beers and two shots of vodka. The first two beers I felt the effects of alcohol and tramadol simultaneously, after the fourth beer it was just the alcohol, tramadol effects completely disappeared. I guess if you don't drink a lot is not that dangerous but it depends on how much you drink.

endingcartAbsolutely. And it is the dose dependence that makes this combination quite dangerous. Because both alcohol and opioid analgesic are representatives of substances whose dosages are quite difficult for many people to control in the process. And the consequences in this case can be very severe.

 

[Gordon Ramsay]

Absolutely. And it is the dose dependence that makes this combination quite dangerous. Because both alcohol and opioid analgesic are representatives of substances whose dosages are quite difficult for many people to control in the process. And the consequences in this case can be very severe.

ParacelsusHey there Sorry to carsh your conversation here but I thought maybe you would be interested in providing a detailed write up on the mix of cocaine and alcohol It is a very common mixture that's even liked by people outside of drug communities and I would like to see your detailed view on the subject

Sorry, didn't meant ti hijack this convo here

 

[Paracelsus]

Hey there Sorry to carsh your conversation here but I thought maybe you would be interested in providing a detailed write up on the mix of cocaine and alcohol It is a very common mixture that's even liked by people outside of drug communities and I would like to see your detailed view on the subject

Sorry, didn't meant ti hijack this convo here

Gordon RamsayHi! No problem and thanks for the question. Here is a topic where the mechanisms and consequences of this combination are described in general terms.

 

[Gordon Ramsay]

Hi! No problem and thanks for the question. Here is a topic where the mechanisms and consequences of this combination are described in general terms.

ParacelsusThank you for pointing me into that direction!

 

[endingcart]

Hey there Sorry to carsh your conversation here but I thought maybe you would be interested in providing a detailed write up on the mix of cocaine and alcohol It is a very common mixture that's even liked by people outside of drug communities and I would like to see your detailed view on the subject

Sorry, didn't meant ti hijack this convo here

Gordon RamsayMaybe I could try it and write down my experience, however it won't be soon, I'm traveling right now and outside my city I don't feel completely safe trying some mixtures. If you wait a month or two I think I could provide a detailed experience.

 

[Gordon Ramsay]

Maybe I could try it and write down my experience, however it won't be soon, I'm traveling right now and outside my city I don't feel completely safe trying some mixtures. If you wait a month or two I think I could provide a detailed experience.

endingcartI have a lot of experience on this mixture but it would be interesting to read more about it from a medical/psychological standpoint

 

[endingcart]

However, and I forgot to write that down, it made my alcohol resistance threshold much lower. After I wrote this I drank two more beers, which would have been my normal drinking on a celebration and I started feeling much more drunk that I normally feel with the same dose. I certainly don't recommend that combination.