What is MDMB-5Br-INACA?
MDMB-5Br-INACA is classified as a synthetic cannabinoid. MDMB-5Br-INACA is used as a precursor in the synthesis of synthetic cannabinoids. It has been sold online as "half finished" synthetic cannabinoids, sometimes as a "chemistry kit" with other compounds required to complete the reaction. This reaction would complete MDMB-5Br-INACA by giving it a "tail" group required for high cannabinoid activity.
Synthetic cannabinoids have psychoactive effects similar to delta-9-tetrahydrocannabinol (THC). However, little to no information is currently known about the activity, potency, and/or toxicity of MDMB-5Br-INACA. New synthetic cannabinoids continue to emerge among the recreation drug supply internationally, seemingly as replacements after a synthetic cannabinoid class-wide ban implemented by China in July 2021 which included most traditional indole and indazole structural scaffolds. Many of these new synthetic cannabinoid analogues are studies with pharmacological and human effects undetermined. Currently, MDMB-5Br-INACA is not a scheduled substance in the United States.
Other precursors lacking a tail chain have also been marketed such as ADB-5'Br-BINACA, ADB-5'Br-BUTINACA, ADB-5-Br-INACA, CH-IATA, ADB-IACA, and ADB-5’Br-EZO-CA. This may be due to increasing legality changes worldwide on synthetic cannabinoids.
Physico-chemical Properties
- Molecular Formula: C15H18BrN3O3;
- Molar mass: 368.231 g/mol;
- Names: methyl (S)-2-(5-bromo-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate; MDMB-5-bromo-INACA; 5Br-MDMB-INACA; Methyl 2-[(5-bromo-1H-indazole-3-carbonyl)amino]-3,3-dimethyl- butanoate;
- Form: solid substance;
- Storage: -20°C;
- Stability: ≥5 years;
Solubility
- DMF: 14 mg/mL;
- DMSO: 14 mg/mL;
- Ethanol: 14 mg/mL;
- PBS (pH 7.2): 0.20 mg/mL;
Legality
In the United States, MDMB-5Br-INACA is unscheduled at the federal level as of May 22nd, 2023.
North Dakota has placed MDMB-5Br-INACA (along with ADB-5'Br-BINACA, ADB-5'Br-BUTINACA and ADB-5-Br-INACA) into Schedule I on 04/27/2023.
North Dakota has placed MDMB-5Br-INACA (along with ADB-5'Br-BINACA, ADB-5'Br-BUTINACA and ADB-5-Br-INACA) into Schedule I on 04/27/2023.
