D-meth article

[Ranof]

An article about methamphetamine isomers and how to separate the right-handed isomer from the left-handed one.

به زودی ترجمه فارسی آنرا قرار میدهم

 

[Ranof]

این محصوله هیدروکلره شده با همین روش هست
اگر رنگ زرد گرفت اصلا مشکلی نداره
میتونید با استن بشورید
و تبلور مجدد کنید

 

[Ranof]

بعد از شستشو ثانویه با استون سرد

After washing with cold acetone

 

[Osmosis Vanderwaal]

There was a fair amount of discussion of the Pope-peachy in the thread following G. Pattons video on seperasting enantiomers with tartaric acid. I don't see the allure, that seems like a shitty yield, I'm pretty sure I do way better than 27% at 90 minutes. I struggle to understand what advantage having 1/2 of your mixture be hcl. Tartaric acid isn't going to dispace that hcl, so It's not going to to have any reaction. Maybe I'm missing something. That's meth?(in rthe picture?)

 

[Ranof]

This is dextromethamphetamine hydrochloride
It gave good yield.
What method do you use for the methamphetamine hydrochloride ?

 

[Osmosis Vanderwaal]

I wouldn't calculate yeild from thast, it's opaque and yellow(?) and doesn't even have a crystalline structure. I dooubt it is more than 70% methamphetamine. The methos I use is just RR tartaric acid (the natural enantiomer) added to meth base in water the Rmeth tartrate precipitates I filter it in a buchner funnel and adjust ph to 7 beofere hcl ing it with a 50% solution of muriatic acid it 5, evaporate to dryness, 3x acetone wash, crystallization. I'm going to have to get some more polarized sheets or find the ones I've got so I can measure the rotation to see what the purity s, but I feel like its 37.5% theroretically

 

[Ranof]

The yellowing disappears after recrystallization
If you proceed with the gaseous hydrochlorination method as you say you will get salt-shaped crystals
If you use the South American method you will get lumpy crystals

And you said you dissolved the methamphetamine base in water and then combined it with what type of tartaric acid?
We use L-tartaric acid

And at the end of each step we measure the purity of the material with a GC device

 

[Osmosis Vanderwaal]

Tartaric acid is the most confusing chiral chemical, and the reason is because it was the first to be discovered to have chirality, so back in whatever 1700's the very first chiral chemical atrtaric acid was assigned l and d, then in it's next reinvention, they switched to L and D and switched. dextrotartaric acid is L-tartaric acid, also knon as the natural enantiomer. We've overcome tjhe ambiguaty by being more specific and the natural form of ta is 1R,2R, or just RR. The laboratory generated enantiomer is 1S, 2S, or SS and 1R,2S and 1S,2R are the mesomers, they are not optically active because they rotate and then rotate back for a net sum of 0 rotation

 

[Ranof]

Very good
I would like to know and make your recipe too

 

[bigbadbear]

عالیه عالی اگر اشتباه نکنم حرارت بالا باعث اکسید و زرد شدنش شده یا نه دلیل دیگه ای داره ؟

 

[Ranof]

اره حرارت بالا در زردی موثره ولی مشکلی برای تبلور مجدد ایجاد نمیکنه چون ناخالصی ها اونجا ازبین می‌ره و تبدیل به شیشه ای میشه

 

[Ranof]

بعد از شستشو شیری رنگ میشود که عکسش رو براتون در ریپلای بالا گذاشتم