JWH-018 synthesis

[WillD]

No video, but I can advise in detail on the process here, private message or XMPP. I have enough practical experience on this synthesis.

 

[dg1533157]

I would like to...

 

[dg1533157]

I would like to

 

[WillD]

If the product does not crystallize from alcohol, you can pour cold water and get a precipitate. The required amount of 018 for herbs depends on the quality obtained and your tolerance. Documented research dosage - 2 mg per hit. But I think more.

 

[Eagle1234]

Thank you very much for responding. It was very helpful information. I appreciate it.
Is it normal for the 3(1-naphthoyl)indole color to turn red when washed with water?

 

[WillD]

Basically on the market, this is reddish

 

[dg1533157]

I'd love to learn...

 

[Yunik777]

Hello my friend, I am not a very good chemist but managed to make jwh and 5f from precursors I buy abroad and I was wondering as I am studying the cannabinoids chemistry if it would be possible to construct cannabinoids from Naphtalene(mothballs)
Also I understand carboxylates and synthetic pyrethroids have very interested properties that can be used to create cannabinoids? Would you have anything to say on that or help me out somehow.? I found out that cypermethrin boosts the effects of cannabinoids.... it's logical cause pyrethroids target the nervous system but I'm sure there's gold to be found there my friend...please reply me someone

 

[WillD]

I think this is not for this topic. We have a lot of research on designer noids. And there are many more classic structures than to think about completely new ones. You can write me your ideas and take part in the design of noids with the team.

 

[itarus1993]

Someone can give me info to buy all things to do jwh-18 EU, i cant find some chemicals PM please

 

[WillD]

listing (click)

You can start with intermediate. Usually suppliers have a complete set for synthesis. There are several methods.

 

[VenditorPulverum]

Hey there,

What is the percentage yield of 3-(1-naphthoyl)indole that you obtained from 1-naphthoyl chloride? I'm curious of this because I am running a similar reaction involving SnCl4. Thanks!

 

[WillD]

Are you using nitromethane for this reaction? It's a must. Stannous chloride anhydrous? Using aluminum chloride is actually easier.

 

[VenditorPulverum]

No I am doing a Friedel-Crafts alkylation of benzene with chloroacetone. I'm using SnCl4. Yes, that nasty fuming liquid because I can't make AlCl3 in great quantities. I was curious what were your yields with this procedure because it's the same reaction after all.

 

[WillD]

The tin of chloride with the indole complex is not dissolved in dcm, you need a sufficient amount of nitromethane so that it is dissolved. This is the main problem. And if you synthesize the catalyst yourself, how do you dehydrate it?

 

[VenditorPulverum]

I make it with dry chlorine gas under anhydrous conditions. Accidental moisture ingress produce only a very tiny amount of pentahydrate crystals, which get left behind after redistillation. Solubility is not a issue in my particular. So do you have a ballpark figure for the percentage yield of the first reaction, based on the 1-naphthoyl chloride? This information would be very useful to me. Thanks!

 

[WillD]

I think you can get about ~75%, although there is other information.