Amfetamiini süntees P2NP-st SnCl2 ja Zn kaudu

[Bigballen]

Kui palju soovitud hapet tuleb lõpus lisada?

 

[blacky2340]

Valage 10 ml atsetooni 1 ml kontsentreeritud 97% + väävelhappe 10:1 suhtega. Kasutage pipetti või süstalt, et tilgutada lahust aeglaselt, kuni saavutatakse pH 5,5. Kui ülehappestatud, lisage rohkem freebaasi, kui kaugelt ülehappestatud ja muutub vedelaks, siis a/b ja uuesti krülistada.

 

[ActionAyi]

Olen mõelnud ka touleeni peale, aga ma arvan, et tiheduse vahe on liiga väike, kas pole ?

 

[G.Patton]

Tere, tänan teid aruande eest! See on tõesti huvitav. 10g amfoonivaba aluse saagis on 80,4%, üsna hea. Kui palju soola saite?

 

[Eleusius_hive_reboot]

i just did this synthesis successfully ! (i was very astonished, that it works, like described...!)

i used 1,7g P2NP

- created sncl2 sol. from h202 and conc HCL first, until total dissolution, quenched oxidizing agent w. Bisulfite.

- dissolved p2np in acetone / EtoH and brought solutions of sncl2/p2np-solvent together in 250ml RBF

vigourously stirred for 2hrs.

------SKIPPED OXIME ISOLATION !!!!! -----

instead gave antoher dash of conc. HCL in to the whole

and gave finely divided active-C powder a hydrogen absorber in to RM.

then three portions of Zn-dust were introduced in several heaps...with subsequent hcl/EtoH addition.

as the reagents were used up i gave a small am. of AcOH to the whole and let it further react out a 15mins.


- now i slowly alkalized to ph 12 (metal precipitates formed immediate and sank...no hassle in base extraction....did with xylene/pet.ether/naphta mixture (+a small emulsion preventing splash of 2-propanol , every extraction step...)


i pooled organic xtracts, washed them with conc.brine f. rocksalt....)

afterwards the washed org.phases were run trough fine filtering apparatus.

added a 100mls of H20 and then titrated with Hcl until ph 5,5 ~


the acidic solution was equiv. mixed with acetone / ethanol-2propanol

with concentration under stirring with surface vent.

then the pasty residue was further refined...

I OBTAINED almost 1,3g amph-hcl (hygroscopic but useable!)

so that is a fine well thought route to go, THANKS TO ORIGINAL MASTERMIND

 

[Eleusius_hive_reboot]

* MAJOR ! update:...

I DID ONE MORE "GOD-MOVE" AFTER THIS SURPRISE RESULT:.....

I SUCCEEDED IN MODIFYING THE SYNTHESIS - AND DID A REDUCTIVE AMINATION

WITH REFINED P2P AND METHYLAMMONIUMACETATE (OR KIND OF)

IT YIELDED METHAMPHETAMINE RACEMATE.... VERY UNEXPECTED QUANTITY- QUALITY AS SAME AS THE USUAL NABH4 ROUTE I PREFERRED BEFORE...


IT WENT DOWN FROM Imine formation -[ACIDIFIED VARIANT]...... TO HYDROCHLORIDE OF SLIGHT PINK APPEARANCE OVER NIGHT !

-->AT ROOM TEMPERATURE<----

PLEASE dont be mad at me but i decided to keep specifics for myself**

it is a whole new approach to phenetylamine syntheses in general ....

CREDITS TO THIS COMMUNITY PRO INSTRUCTIONAL P2P PURIFICATION TUTORIALS / I WENT TROUGH THE HASSLE OF THE WHOLE WORKUP TECHNIQUES OF THE BB-gate wisdom ...

THE PHENYLACETONE I DERIVED BY : Fe/H+ --P2NP---> Phenyl-2-Propanone


**(exception 4 you, Patton ..i made a writeup , documenting specs etc. i think you get what these
synthesis-dynamic principles hold in value )

 

[TucoSalamanca.]

Sain 5 grammi amfetamiini 15 grammi p2np-st.

 

[Chemdogkm]

u recomend this reaction? Or the aluminum? Or the copper?

 

[sandman]

Ma ei usu, et see toimib. Ma loodan, et töötab ja pean seda proovima.

 

[TucoSalamanca.]

Ma loodan, et teil õnnestub, sõber, mul ei õnnestunud.

 

[TucoSalamanca.]

Kas te olete seda meetodit

 

[mithyl2]

Ma olen teinud borohüdriidi meetodit mitu korda ilma eduta. kõige lähemale jõudsin, kui tegin umbes 0,2% amfetamiini saagist. see oli siiski reaalne. mul on väga vaja, et see töötaks, ja see ajab mind täiesti hulluks. andke meile teada, kuidas dcm läheb.

 

[TucoSalamanca.]

Ma kirjutan, mu sõber, ärge jätke oma palveid vahele, et see süntees saaks teostatud, aitäh.

 

[TucoSalamanca.]

Ma ei saanud täna sünteesida, teen seda homme ja annan aru.

 

[ActionAyi]

kas ekstrakti jaoks on olemas mõni muu viis kui DCM ?
Võib-olla n-heksaan ?

 

[August]

Tere sõbrad, kas see reaktsioon ei tekita lihtsalt fenüületüülamiini (PEA) või olen ma lihtsalt rumal (suur võimalus)

 

[William D.]

Part of this method allows you to get phenylacetone. But stage 2 can be difficult.

 

[Amin. M]

Tere, mu sõber
Lugesin teie kommentaari ja mulle meeldis see
Kuidas saite puhast amfetamiini (teises etapis)?
Palun andke nõu, milline meetod amfetamiini tootmiseks on parem ja lõppkokkuvõttes on suurem puhtusprotsent
Ja et ta hankis tooraine läbi poe
(mul ei ole professionaalset laboratooriumi)

 

[michelAMPH]

Zonder de kosten van 300 gram P2NP .
alle grondstoffen voor 200 gram amfetamine free base kosten hier €416,68???
Mooi recept alleen het kan totaal niet uit