Quelle est la meilleure synthèse de la méphédrone (4-MMC) ?

[PabloEscobar]

J'ai fait des recherches sur le forum et j'ai constaté qu'il existait de nombreuses façons différentes de produire de la méphédrone. Selon vous, quelle est la synthèse qui offre un très bon rendement, qui est assez simple et qui est moins susceptible d'être détectée ?

 

[G.Patton]

Cela dépend de vos réactifs de départ. Les bonnes méthodes consistent à utiliser le 2-brormo ou le 2-iodo-4'-méthylpropiophénone.

 

[mrreese]

e pouvez-vous nous dire ce qu'il faut faire si le 4méthypropiophénone est réglementé ?

 

[HIGGS BOSSON]

Dans ce cas, vous pouvez choisir les options suivantes :
1. Clarifier si le bromo (BK-4) ou l'iodocétone (IK-4) est légal et, si c'est le cas, commander la substance en Chine.
2. Synthétiser vous-même le 4-méthylpropiophénone (la synthèse se trouve sur le forum).
3. Remplacer la 4-méthylpropiophénone par la 3-chloropropiophénone ou un autre analogue.

 

[G.Patton]

Je ne peux pas vous dire ce qu'il faut faire.

 

[Nsowonxmd]

Où le moins. Vous êtes en train de regarder.
Où le plus. Vous trouverez

 

[QAZ123123]

2-Bromo-4'-methylpropiophenone (cas 1451-82-7) Making 4MMC，The simplest synthesis method?

 

[dnBQByvHb8Zkawbjpx]

It's not like there's too many options.

React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.

The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.

Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.

 

[QAZ123123]

Can you give me a recipe and production process?I haven't experimented yet.I need to decide on my plan now.Then start，Thank you

 

[dnBQByvHb8Zkawbjpx]

Bro there's like 20 posts with recipes about this on the forum. Read them, compare them, see the different solvents that people use and find which you can get the easiest based on your circumstances, and come back with any concrete questions that you might have. But you need to put in your own time and work first, nobody can do that for you.

 

[QAZ123123]

Thanks for your suggestion, I will read it. Are all the methods in those videos feasible? Then I just follow the video step by step

 

[dnBQByvHb8Zkawbjpx]

Yes, all of them are feasible. Just pay attention to the details. Some videos use iodoketone while the majority of posts use bromoketone that is typically easier to source. But even then the process tends to be the same.

Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.