ghb synthesis

Copied from the clear web. ingredients: Methanol, Gamma-valerolactone (GVL) Sodium Hydroxide (Lye) Equipment: Beaker Vacuum filter Pyrex dish Synthesis: I started off by putting ( 40ml of methanol ) in a beaker and added ( 6 gr sodium hydroxide) to it, the heating was put to low and stirring...

Starting reagents and materials 100 ml H2O 7.21 g THF 15.1 g KBrO3 13.6 g KHSO4 14 g Na2S2O5 dissolved in 150 ml H2O 150 ml H2O 250-300 ml DCM 50 g Na2SO4 3.38 g NaHCO3 dissolved in 15 ml H2O 3-neck flask 1000 ml Thermometer High efficiency double circuit reflux Magnetic stirrer Cold...

Introduction. This file deals with the synthesis of GHB and related compounds. It is highly dangerous to attempt a synthesis of GHB without the proper knowledge of practical organic chemistry. The far most simple way to produce GHB is by the hydrolysis of the corresponding lactone (a cyclic...