hydrogenation

Hello there, Currently working with some collaborators to set up production of MDMA at considerable scale. It seems that anything beyond maybe a few kilos at a time requires a proper high-pressure setup for catalytic hydrogenation. Of course this is quite sophisticated and hazardous work...

Has anybody ever had any luck with this process? I’m confused about the part where it says to add two drops of concentrated sulfuric acid to the ephedrine/acetic acid mixture but it also says to make sure no water is in the reaction mixture. Doesn’t concentrated sulfuric acid contain water? Also...

MDA Hi! One could be looking for advices for synthesizing MDA from PMK. PMK- ethyl glyc. -> PMK Q1) Could/should one vacuum distill PMK to purify? Anyone knows PMK distill temp at vacuum pump level vacuum? Then reductive amination of PMK with anhydrous ammonia and hydrogen in presence of...

Introduction Gaseous hydrogen used in laboratory practice as a reducing agent. Some reduction reaction in drug manufacturing using Hydrogenation procedure such as reduction of P2NP to Amphetamine, Dezocine (Dalgan), Levorphanol and Racemorphan syntheses. Hydrogen gas can substitute hard-to-reach...