14-methoxymetopon has anyone ever heard of this? (oxymorphone related?)

[JustFuckMyShitUpFam]

I just read a thread on the opioid RC subreddit about this chemical.

Isn't a nitazene from what I know and is related to oxymorphone from the extremely limited research I have done. It seems not a lot is known about it either.

Does anyone here know more about it? Seems very potent and interesting and much better than zenes from what I saw in the short time I have read about it.

Thanks for any info!

 

[JustFuckMyShitUpFam]

14-Methoxymetopon is an experimental opioid drug developed by a team led by Professor Helmut Schmidhammer at the University of Insbruck in the mid 1990s.[1] It is a derivative of metopon in which a methoxy group has been inserted at the 14-position. It is a highly potent analgesic drug that is around 500 times stronger than morphine when administered systemically; however, when given spinally or supraspinally, it exhibits analgesic activity up to a million fold greater than morphine.[2] It binds strongly to the μ-opioid receptor and activates it to a greater extent than most similar opioid drugs.[3] This produces an unusual pharmacological profile, and although 14-methoxymetopon acts as a potent μ-opioid full agonist in regard to some effects such as analgesia, a ceiling effect is seen on other effects such as constipation and respiratory depression which is believed to involve interaction with the κ-opioid receptor[4]