3-CMC Synth for a Newbie

[lheartamines]

Hi Everyone! I'd like to synth 3-cmc for personal use. I've become quite fond of it, but can no longer obtain it (constant fraud / poor substitutes). I have a little bit of organic chemistry experience, such as simple acid base extractions, etc. I've perused this forum and there are several posts regarding this synth, but I couldn't find a solid writeup, Just dead threads and links to other posts that were not easy to follow for a newb like myself.


Here are the reagents I've accumulated so far for my project:
2-Bromo-3'-chloropropiophenone (liquid form)
Dichloromethane
Acetone
Methylamine
HCL 32%

Can someone lead me to a good writeup or possibly video?

Also, I anticipate I'll make mistakes the first or second time I'll go through this process. So to not waste my reagents as I practice, what are some good minimal amounts to start of with, specifically with the 2b3c? Can I start as low as 5 or 10 ml ? Then adjusting the rest via molar weight?

Thanks in advance!!!

 

[Goku]

Hi Everyone! I'd like to synth 3-cmc for personal use. I've become quite fond of it, but can no longer obtain it (constant fraud / poor substitutes). I have a little bit of organic chemistry experience, such as simple acid base extractions, etc. I've perused this forum and there are several posts regarding this synth, but I couldn't find a solid writeup, Just dead threads and links to other posts that were not easy to follow for a newb like myself.


Here are the reagents I've accumulated so far for my project:
2-Bromo-3'-chloropropiophenone (liquid form)
Dichloromethane
Acetone
Methylamine
HCL 32%

Can someone lead me to a good writeup or possibly video?

Also, I anticipate I'll make mistakes the first or second time I'll go through this process. So to not waste my reagents as I practice, what are some good minimal amounts to start of with, specifically with the 2b3c? Can I start as low as 5 or 10 ml ? Then adjusting the rest via molar weight?

Thanks in advance!!!

lheartamineswith dcm u dont do it

 

[lheartamines]

with dcm u dont do it

GokuDoes 2b3c react with DCM? Is that why DCM should not be used? Is Toluene a better solvent? If not Toluene, what other solvent should be used?

 

[Goku]

Does 2b3c react with DCM? Is that why DCM should not be used? Is Toluene a better solvent? If not Toluene, what other solvent should be used?

lheartaminesu use 2 solvate to made it

 

[lheartamines]

u use 2 solvate to made it

GokuWhat are the two solvents? Are they any of chloroform, ethyl acetate or methanol?

 

[Sjeik]

There is no clear explanation on the 2b3c conversion on this forum, iv searched through al but the only thing written is that Its the same conversion as 2b4m..

 

[Goku]

There is no clear explanation on the 2b3c conversion on this forum, iv searched through al but the only thing written is that Its the same conversion as 2b4m..

Sjeikis not the same made u will see is bulshit

 

[Sjeik]

is not the same made u will see is bulshit

GokuI know

 

[itcantbereal]

Genuinely curious, what is the appeal of 3cmc? I've been looking for real 4mmc across Europe this year (last year was no problem) and have only found 3cmc which is a pretty nasty compound in all the different batches i've tried. What am I missing about the appeal of this one?

 

[Goku]

Genuinely curious, what is the appeal of 3cmc? I've been looking for real 4mmc across Europe this year (last year was no problem) and have only found 3cmc which is a pretty nasty compound in all the different batches i've tried. What am I missing about the appeal of this one?

itcantbereal3cmc is still legal in nederland and is a lot in all europe 4mmc is much more hard found

 

[lheartamines]

Genuinely curious, what is the appeal of 3cmc? I've been looking for real 4mmc across Europe this year (last year was no problem) and have only found 3cmc which is a pretty nasty compound in all the different batches i've tried. What am I missing about the appeal of this one?

itcantberealI enjoy it only In very small microdosing quantities. ~30mg. It's closely related to a popular antidepressant Wellbutrin. I don't think it's a good substance to get seriously geeked on.

 

[lheartamines]

Well according to other sources, DMSO would be a good solvent to use. I will try it and report back.

 

[Researcherr]

Which 2 solvents?
Can anyone just share this ''top secret'' solvent thing

 

[Jesse_Pinkman_]

so, my experience is,
100g 2b3c
300dcm
200methylamin40% aqua
3 hours stirring
I use a sealed glas 1,8l, put foil between lid and glass so that nothing smells or gas escapes.
After reaction took place
2 times washing with dest.water
1 time extract water phase with dcm
put into rm,
add same amount fresh water into rm
put on magnetic stirrer
acidificaction drop by drop till ph6, about 50-55ml HCI,
after that take the water layer,evaporate , let it crystallize, takes some time
opt. rotovap till 50% of the water is gone, then air drop


ethylacetat is possible, takes only 20 min, no heating necessary, rest same prosedure like with dcm

 

[acidtobase125]

so, my experience is,
100g 2b3c
300dcm
200methylamin40% aqua
3 hours stirring
I use a sealed glas 1,8l, put foil between lid and glass so that nothing smells or gas escapes.
After reaction took place
2 times washing with dest.water
1 time extract water phase with dcm
put into rm,
add same amount fresh water into rm
put on magnetic stirrer
acidificaction drop by drop till ph6, about 50-55ml HCI,
after that take the water layer,evaporate , let it crystallize, takes some time
opt. rotovap till 50% of the water is gone, then air drop


ethylacetat is possible, takes only 20 min, no heating necessary, rest same prosedure like with dcm

Jesse_Pinkman_Hi I'm very glad you are sharing your experience I have a few questions

What is the efficiency of this method ?

Is it possible to transfer it to plastic barrels to scale up to kilograms of finished product if so how to do it ?

For the help received, I will be happy to repay you when everything at my place starts greetings

 

[PolandoEmingarnte]

Hi I'm very glad you are sharing your experience I have a few questions

What is the efficiency of this method ?

Is it possible to transfer it to plastic barrels to scale up to kilograms of finished product if so how to do it ?

For the help received, I will be happy to repay you when everything at my place starts greetings

acidtobase125he say he get 200g form 1l 2b3ch is real low %.
in poland they made on tons and somebody say u need 2 solvents for an excellent yield of 70%+
plastic barrels can be filled with a maximum of 2/3 of the volume of 100 l barrels can be made up to a few kg and the crystallization time on a large scale is a few weeks

 

[PolandoEmingarnte]

Hi I'm very glad you are sharing your experience I have a few questions

What is the efficiency of this method ?

Is it possible to transfer it to plastic barrels to scale up to kilograms of finished product if so how to do it ?

For the help received, I will be happy to repay you when everything at my place starts greetings

acidtobase125to get crystal like glass u need wash it real good

 

[Sjeik]

to get crystal like glass u need wash it real good

PolandoEmingarnteLol, this picture is 3cmc of india.

 

[sierraleone]

Lol, this picture is 3cmc of india.

Sjeik>india
>Straigh out of methylamine 40% ganges water solution.

 

[Jesse_Pinkman_]

1 Liter is 1,5kg, but i dont know about 2 solvents, 100g = 20g crystals ,yes it is very low and frustrating but if you read the forum, everbody says it is easy, same way as 4-mmc, but never saw that someone really explains how he gets the final product.

 

[PolandoEmingarnte]

1 Liter is 1,5kg, but i dont know about 2 solvents, 100g = 20g crystals ,yes it is very low and frustrating but if you read the forum, everbody says it is easy, same way as 4-mmc, but never saw that someone really explains how he gets the final product.

Jesse_Pinkman_somebody who made it on big scale no share with other people because is biznes much lab low price for product simple