4CMC

[Rush-Benzo]

Hi. With 4CMC how many L of m40 to give for 1kg of 2bromo4chloropropiophenone? Acidification standard hydrochloric acid + acetone / ethyl acetate to pH 5-6? For toluene 2h and 60 degrees will be ok?

 

[hexen]

Hi. With 4CMC how many L of m40 to give for 1kg of 2bromo4chloropropiophenone? Acidification standard hydrochloric acid + acetone / ethyl acetate to pH 5-6? For toluene 2h and 60 degrees will be ok?

Rush-BenzoNo synthesis 3cmc 4cmc is other way like mmc is no the same

 

[Rush-Benzo]

Anything more specific?

 

[HerrHaber]

even the molar masses are the same, the only difference is in the potency of the resulting compound (I guess)

 

[hexen]

even the molar masses are the same, the only difference is in the potency of the resulting compound (I guess)

HerrHaberBro dont say bulshit is no the same

 

[HerrHaber]

Bro dont say bulshit is no the same

hexenmolarity or effect?

 

[hexen]

molarity or effect?

HerrHaberWhat i dont Understend u

 

[HerrHaber]

the molecular mass of both 4-chloromethcatinone and 3-cloromethcatinone are identical, the fact that the position of the halogen on the aromatic moiety is different (para vs meta) results in a different change ellicited in the target protein it binds to (be it conformational, affinity or just different docking), you are true they are not the same effect wise but from a synthetic standpoint the procedure is identical even though it starts from different precursors (4-chloropropiophenone and 3-chloropropiophenone respectively). I hope this was clear enough, if not, you may consider reading some basic not necessarily drug related organic chemistry like most of us already did.

 

[hexen]

the molecular mass of both 4-chloromethcatinone and 3-cloromethcatinone are identical, the fact that the position of the halogen on the aromatic moiety is different (para vs meta) results in a different change ellicited in the target protein it binds to (be it conformational, affinity or just different docking), you are true they are not the same effect wise but from a synthetic standpoint the procedure is identical even though it starts from different precursors (4-chloropropiophenone and 3-chloropropiophenone respectively). I hope this was clear enough, if not, you may consider reading some basic not necessarily drug related organic chemistry like most of us already did.

HerrHaberMade u will see is no easy made if u dont know chemistry

 

[m924]

I've got a question, if you had the choice between synthesizing the MMCs or the CMCs why would you ever pick CMC? with how neurotoxic it is and the fact that 4CMC is illegal too it doesn't make any sense. 3CMC maybe just because it's legal but besides that you're better off with just going to synthesize 3/4MMC

 

[sleeplessmania]

I've got a question, if you had the choice between synthesizing the MMCs or the CMCs why would you ever pick CMC? with how neurotoxic it is and the fact that 4CMC is illegal too it doesn't make any sense. 3CMC maybe just because it's legal but besides that you're better off with just going to synthesize 3/4MMC

m924Everyone always has a choice, but the choice is decided for or against by outer factors.

"why would you ever pick CMC?"

Simply answered, cause the para-halogenation it is subjectively from my experience a way rushier and actually stimulating substance than 4-MMC. I "only" done 3-CMC and 4-MMC (3-CMC in total in the kilograms range, and 4-MMC not as much but to a way lower tolerance each redose overdoses, not to say to follow this, but learn from my mistakes and prevent them)

"with how neurotoxic it is"

Well the stigma around para-halogenated methcathinones is extremely huge and wrong misconception, everything is, some less and some more, but it is calculable. To my knowing, there is not a single research paper that would state that para-halogenation in methcathinones increased the neurotoxicity as to the MMC's, both being way less destructive than compared to desoxyephedrine[methylamphetamine] or MDMA.

The research papers that state severe neurotoxical damage from these compounds made the experiements with such dosages of 4-CMC that would be in the lethal zone anyways, and of course then the neurotoixicity will be severe.

Longer period time of binging ANY drug will result in severe neurotoxical, cystoxical, and in general damage done to the human body and brain. Everyone's neurochemistry and biology and other factors differ from each other, meaning the results will be also highly different from patient to patient

"fact that 4CMC is illegal too it doesn't make any sense."

Most of the times, talking about Eastern European areas, the main view on these substances are not even close to legality, as it's being sold on the streets mainly due to a huge demand and crisis, under various names. The percentage of people who purchase 3-CMC for the law status it falls into are very shallow.

"you're better off with just going to synthesize 3/4MMC"

Everyone should decide what their personal preference is based on their experiences, some people will prefer MMC's and some the CMC's or EMC's or MEC's, it's impossible to say what is better of, only not if you talk about your own personal preference.