SYNTH OF A-PHP

[petetheplant1]

Been looking into synthesis of A-PHP does anyone know if it is possible for a complete beginner to do

 

[WillD]

If there is access to the necessary reagents, then no problems

 

[petetheplant1]

i have a couple of guides to making the reagents needed was really hoping there would be source on here you could buy them from

 

[WillD]

alpha-bromovalerophenone (click)
This is an intermediate for A-PVP, not a bad variant to start. Just one reaction with pyrrolidine. In addition, the solvent for the reaction (several variants) and acid (hydrochloric acid aq.soln)

alpha-bromovalerophenone
pyrrolidine
benzene (or another solvents)
HCl cons. aq. soln
acetone (desirable)

one-step reaction, using water we can receive crystals immediately

 

[Morpheus77]

T

alpha-bromovalerophenone (click)
This is an intermediate for A-PVP, not a bad variant to start. Just one reaction with pyrrolidine. In addition, the solvent for the reaction (several variants) and acid (hydrochloric acid aq.soln)

alpha-bromovalerophenone
pyrrolidine
benzene (or anoter solvents)
HCl cons. aq. soln
acetone (desirable)

one-step reaction, using water we can receive crystals immediately

William DampierThat link isn’t working for me, although it might not be meant for me lol. Sorry, I’m new here. I’ve been trying to find as much info as possible for my go at an a-php run. Bromination is a bit of a chore, so if the valero or Hexano variant can be obtained, already brominated, that would be awesome Although I’m not sure about the stability of those compounds, so idk if obtaining them from outside my own lab would be doable

 

[WillD]

That link isn’t working for me, although it might not be meant for me lol. Sorry, I’m new here. I’ve been trying to find as much info as possible for my go at an a-php run. Bromination is a bit of a chore, so if the valero or Hexano variant can be obtained, already brominated, that would be awesome Although I’m not sure about the stability of those compounds, so idk if obtaining them from outside my own lab would be doable

CptnCrunchlink (click)

 

[Morpheus77]

link (click)

William DampierThank you!

 

[kiddgr0tesk86]

So I have thousands of morphine sulfate immediate release tabs and mscontin 200mg, and I just drop the sulfate pentahydrate salt off the morphine ending up with pure morphine base, then converted to morphine hcl, and ran with that my fav accomplishment is the successful synth of vilan ™ (aka nicomorphine hcl)

 

[kiddgr0tesk86]

So I have thousands of morphine sulfate immediate release tabs and mscontin 200mg, and I just drop the sulfate pentahydrate salt off the morphine ending up with pure morphine base, then converted to morphine hcl, and ran with that my fav accomplishment is the successful synth of vilan ™ (aka nicomorphine hcl)

kiddgr0tesk86Very rewarding

 

[Morpheus77]

So I have thousands of morphine sulfate immediate release tabs and mscontin 200mg, and I just drop the sulfate pentahydrate salt off the morphine ending up with pure morphine base, then converted to morphine hcl, and ran with that my fav accomplishment is the successful synth of vilan ™ (aka nicomorphine hcl)

kiddgr0tesk86Care to share your route to nico?