Methylphenidate from ritalinic acid?
- Thread starter iamaturtle
- Start date
Google Scholar has several, for instance
WO2012080834A1 - Low-temperature synthesis of methylphenidate hydrochloride - Google Patents
The present invention describes a process for the preparation of methylphenidate hydrochloride. The process involves the esterification of ritalinic acid and methanol in the presence of an acid catalyst at a low temperature. The process may optionally involve the addition of an orthoester.
patents.google.com