Complete MDMA synthesis from Sassafras oil with Al/Hg

[candymanspieler]

Help out a noob. Is it safe to say that safrole is the best precursor in terms of being efficient and not with too many reagents? I would thing that starting from something else would be a lot more expensive in terms of the chemicals you have to aquire?

 

[BevItUp]

If you never lost four days of your life completely enmeshed in a website, here's your opportunity.

An open web index containing, if not everything, certainly an overwhelming amount of, information, knowledge, and experience. If you get something out of it, and I know you will; be sure to leave a donation so Earth Erowid can continue providing this exceptional resource. Yes, apparently the name of the founding director is Earth; which seems coherent and intrinsically satisfying somehow.
https://www.erowid.org/archive/rhodium/chemistry/index.html

Check out some of the other directories of the URL path, because they have extensive written material on all related subject matter. It's a somewhat unsettling amount of knowledge; most of which is original, and the real first hand experiences a lot of people. Much of the detailed information won't be found anywhere else, and there's some really useful knowledge to be had.

A tangent:

While looking for the link, I ended up reading some stuff on their forum, and I noticed right away that 20-25 years ago people said and posted whatever they wanted. Some were careful about what they posted, but most had a "Fuck you. I'll say whatever I want to say" attitude. It occurred that our collective governments have slowly, a little at a time, made us less resistant and more likely to comply. Hmm; I guess I'm a sheep after all

 

[William D.]

PMK glycidates -> PMK oil

 

[Hermit]

what is the quantity of Peracid used?

 

[Chemtrail]

NAMES AND SYNTHETIC ROUTES TO MDMA

Enjoy

 

[Anarchy Labz]

Could you make MDA by doing a reductive amination with ammonia and Al/Hg? I saw Shulgin used ammonium acetate but that is a bit hard for me to get, an easier way for me would be to ammoniate isopropanol (methanol is unavailable for me) by gassing it and then use it for the reaction. If the answer is yes, would it be better to add the MDP2P dropwise or all at once?

 

[Anarchy Labz]

Wassink et al., A Synthesis of Amphetamine. J. Chem. Ed., 51, 671 (1974). Amphetamine was obtained in a one step synthesis. Although the yield of the reaction was not as high with reduction utilizing ammonia instead of methylamine (30% yield versus 70%), the easiness of the procedure made the method worthwhile. Note that it may be possible to recover unreacted phenyl-2-propanone from the initial ether extract. A mixture of 40 g. (0.3 mole) phenyl-2-propanone, 200 ml ethanol, 200 ml 25% ammonia, 40 g. (1.5 mole) aluminum-grit and 0.3 g. (0.001 mole) mercuric chloride (HgCl2) was warmed with vigorous stirring until reaction took place, after which warming was stopped immediately. Cooling was applied if the reaction became too violent. When the violence of the reaction had diminished, the mixture was refluxed with vigorous stirring for about 2 hours, concentrated in vacuo to 200 ml and poured into ice water, alkalinized with 120 g. potassium hydroxide (KOH), and extracted with diethyl ether. The extractions were shaken with 20% HCl (pressure), the resulting water layer alkalinized (e.g., with 50% sodium hydroxide) and then extracted with 150 ml ether. The organic layer was dried over Na2SO4 (sodium sulfate; KOH is probably a better choice), the ether evaporated and the residue distilled in vacuo. Yield: 12.5 g. (0.09 mole or 30% of theoretical yield). Preparation of amphetamine sulfate yielded 96-98% product with a purity of 99.2-99.8% according to the USP.

 

[Chemtrail]

It would be cool if someone made a "how - to " video of this procedure

Either the peracid epoxide oxidation
Or
Wacker oxidation with p-benzoquinone
Or both