Hello members, i was recently interested in synthesis of AMT and the easiest way i think is from indole-3-aldehyde (made from vilsmeier haack) by henry reaction followed by reductive ammonolysis.
So the thing is i was wondering that i could make tryptamine doing same, I just want to know your views on formation of beta-carbolines during reduction how much are they produced and tryptamine being pretty sensitive molecule might cyclize during reduction, currently to get tryptamine i decarboxylate tryptophan
So the thing is i was wondering that i could make tryptamine doing same, I just want to know your views on formation of beta-carbolines during reduction how much are they produced and tryptamine being pretty sensitive molecule might cyclize during reduction, currently to get tryptamine i decarboxylate tryptophan