Mescaline Synthesis With Nitromethane. 1000g Scale.

malesh67482

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Does this synthesis work for 2,5 dimethoxbenzaldehyde? Is the reduction using NaBh4 and copper chloride still the best way for reduction? And then the cleanup using oxalic acid?
 

Rabidreject

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Yes, is a great way to reduce nitroalkene’s. From what I understand it’s just 4-haloginated aldehyde’s that it kicks off, which is why people tend to brominate or iodinate or whatever from 2c-h
 
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