New method to be tested
A method for the production of lysergic acid diethylamide (LSD), comprising the steps of; a. preparing a suspension of lysergic acid hydrate in ethyl acetate; b. addition of diethylamine under protective gas atmosphere; c. addition of propane-phosphonic acid anhydride solution (T3P) in ethyl acetate; d. stirring of the mixture under protective gas atmosphere for at least 4 hours; e. stopping the reaction by dilution with ethyl acetate; f. extraction with water; g. drying of the organic phase over a desiccant at 20-60°C and under vacuum; h. obtaining a crude product containing lysergic acid diethylamide (LSD)
A method for the production of lysergic acid diethylamide (LSD), comprising the steps of; a. preparing a suspension of lysergic acid hydrate in ethyl acetate; b. addition of diethylamine under protective gas atmosphere; c. addition of propane-phosphonic acid anhydride solution (T3P) in ethyl acetate; d. stirring of the mixture under protective gas atmosphere for at least 4 hours; e. stopping the reaction by dilution with ethyl acetate; f. extraction with water; g. drying of the organic phase over a desiccant at 20-60°C and under vacuum; h. obtaining a crude product containing lysergic acid diethylamide (LSD)