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3'-Methylpropiophenone and hexanophenone synthesis

Roberto Cofresí

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Can somebody explain the : 3'-Methylpropiophenone synthesis(large scale) .
Hexanophenone synthesis(large scale) from benzonitrile
Thanks , Kind regards
Roberto
 
Last edited:

G.Patton

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Hello, it is better to buy these reagents. Do you need them?
 

Roberto Cofresí

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Hello @G.Patton , I`m more intrested in the synthesis of these 2 reagents more than buying them directly. Thank you

For example for valerophenone snynth is used n-BuMgCl what about for hexanophenone?
 

G.Patton

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Hello @G.Patton , I`m more intrested in the synthesis of these 2 reagents more than buying them directly. Thank you

For example for valerophenone snynth is used n-BuMgCl what about for hexanophenone?
Roberto Cofresí
You have to use hexanenitrile istead of valeronitrile (pentanitrile) and PhMgBr Grignard reagent for hexanophenone synthesis.
R4Uj3MuQvk
 
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