Phenylacetone (P2P) synthesis from benzaldehyde with butanone

[TheNut22]

I have washed my P2P 2 times, and it is still red coloured when all of it (~20 ml) it sits in my measuring flask.
When it was in my pyrex dish, it was clear coloured, and when it was stuck in the instrument I was taking it out it was yellow coloured.
Is this normal? It is in oil form, and the smell is very honey-like.

 

[ZMI_AA0B]

I have washed my P2P 2 times, and it is still red coloured when all of it (~20 ml) it sits in my measuring flask.
When it was in my pyrex dish, it was clear coloured, and when it was stuck in the instrument I was taking it out it was yellow coloured.
Is this normal? It is in oil form, and the smell is very honey-like.

TheNut22When I introduce hydrogen chloride, it also turns red

 

[TheNut22]

Think about adding water before starting the process.

WillDAdding water to Leuckart? No. Or why?

 

[TheNut22]

This is normal, the fact that it becomes red. With recrystallization with ethanol, this can be purified

WillDI have gradually heated now for about 5 hours. My reaction temperature has been 160 C now for about 3 hours (my digi-meter is outside the flask). I'm ready for 24 hour reaction, but what do you think, how many hours should I heat this. I have AlCl3 catalyst, formamide, my P2P and formic acid in there with boiling stones.

 

[TheNut22]

Now it has been about 25 hours ~ 155 C, but I'm still not finished.
Good bubbling still going.

 

[TheNut22]

Now it has been about 25 hours ~ 155 C, but I'm still not finished.
Good bubbling still going.

TheNut22I finished refluxing at 27:th hour. What I was left is black very thick oil, that smells like amine. Just waiting tomorrow to get my solutes to proceed.

 

[ZMI_AA0B]

Teacher, if my device only has a 1000ml device, how should I proceed

 

[G.Patton]

Teacher, if my device only has a 1000ml device, how should I proceed

ZMI_AA0BCan u reformulate your question correctly? It's not understandable.

 

[ZMI_AA0B]

Can u reformulate your question correctly? It's not understandable.

G.PattonMy instrument only has a maximum of 1000ml, and I have all the experts in this synthesis method. Only you can reply to me. Thank you. I am extremely grateful

 

[ZMI_AA0B]

Step 2: 10 liters of acetic acid will fill the flask. How can other solvents still be filled

 

[TheNut22]

Step 2: 10 liters of acetic acid will fill the flask. How can other solvents still be filled

ZMI_AA0BWhy you are on this forum, or this website? I'm just curious.

 

[ZMI_AA0B]

Why you are on this forum, or this website? I'm just curious.

TheNut22I want to learn how to synthesize phenylacetone in the synthesis of amphetamine

 

[TheNut22]

I want to learn how to synthesize phenylacetone in the synthesis of amphetamine

ZMI_AA0BWell, what can I say. At first I recommend to you , is to read some chemistry books, like Uncle Fester Secrets of Methamphetamine Manufacture vol.8. Start from there. Read, and learn, so you don't have to ask any basic questions, that many of us won't bother to tell you, because answering those kind of basics would take so much time that it becomes work. So, you have to read, to even think about manufacturing amphetamines.

 

[ZMI_AA0B]

Well, what can I say. At first I recommend to you , is to read some chemistry books, like Uncle Fester Secrets of Methamphetamine Manufacture vol.8. Start from there. Read, and learn, so you don't have to ask any basic questions, that many of us won't bother to tell you, because answering those kind of basics would take so much time that it becomes work. So, you have to read, to even think about manufacturing amphetamines.

TheNut22Thank you very much for your guidance, teacher

 

[ZMI_AA0B]

I have found many methods for synthesizing phenylacetone, only this method. I only have the materials, but the instrument is only 1000ml. Can the teacher teach me