Amphetamine synthesis from P2NP via Al/Hg (video)

[ACAB]

--Sorry, but edit time was over--

But for the amalgam reaction, alcohol is certainly the best choice. But not for crystallization, if its volume is large on the amount of the base of amphetamine.

William DampierAnd a second thing that makes a question mark shine over my head. In the synthesis we use IPA and after the addition of NAOH an upper layer is formed consisting of IPA/amphetamine, to this layer we add the acid. Why don't we remove the IPA first and then switch to acetone?

 

[ACAB]

When there is a large amount of alcohol, the powder is poorly crystallized. Amphetamine is almost not dissolved in cold acetone (unlike alcohol), and even the usual adding acetone to alcohol crystallizes powder in seconds. No need to misinform people.

William Dampier

But for the amalgam reaction, alcohol is certainly the best choice. But not for crystallization, if its volume is large on the amount of the base of amphetamine.

The safety data sheet from amphetamine sulfate says poorly soluble in ethanol 96%, then this should also apply to isopropanol and methanol, shouldn't it?
The info confuses me right now, because in practice plenty of sulfate precipitates also in IPA.

And a second thing that makes a question mark shine over my head. In the synthesis we use IPA and after the addition of NAOH an upper layer is formed consisting of IPA/amphetamine, to this layer we add the acid. Why don't we remove the IPA first and then switch to acetone?

@William Dampier can you please explain, i want to know it exactly. Until now I always assumed that isopropanol, acetone or methanol and ethanol are almost equally suitable, because the sulfate is poorly soluble or not soluble at all in all of them, which is why I am now surprised. You can also answer me by conversation if this would get out of hand, but please give me an explanation.

 

[WillD]

In a large amount of isopropyl alcohol, a small amount of amphetamine of salt will not crystallize until it is diluted with acetone or evaporate alcohol. If the amount of alcohol is small, then there are no problems. This is a remark, not an axiom. It all depends on concentrations, but if you need to get the maximum, I said above.

 

[ASheSChem]

0:46-2:36 - Amalgam of mercury nitrate. Amalgamated aluminium will reduce 1-phenyl-2-nitropropene to amphetamine. During the amalgamation reaction: little gas evolves, a grey precipitate is formed. It is important not to miss the moment when the aluminium is ready: this can be determined by the formation of a grey precipitate and by the increased gas evolution; this happens in 10-15 minutes after the load.
The water is drained without removing the gauze, the amalgamated aluminium is washed with two portions of cold water

HIGGS BOSSONwhen you wash aluminium with water, we need to wash it until to have a clear water ?
every wash water are more clear, but after 2 or 3 wash it always little grey

 

[ACAB]

In a large amount of isopropyl alcohol, a small amount of amphetamine of salt will not crystallize until it is diluted with acetone or evaporate alcohol.

William DampierThat's good to know, that will be my advice in the future. I will also rinse the extracted amphetamine with acetone so as not to increase the amount of IPA. It is hard to reduce the amount of IPA in the separated phase. Rinsing the filter only with water or also with acetone can be done. The two solvents cannot be separated optimally, but the IPA in the acetone can be converted to acetone after recovery, for which I have instructions.

 

[Honolulu98]

Hello I watch your video and thought it was excellent, but does anyone know where I can order mercury nitrate from and get delivered to the UK ? Thanks

nitochronic1
The mercuric chloride was just as valid for me. It may be easier for you to get. Getting nitrate cost me a lot in Spain, but chloride worked just as well.

Although I also bought some mercuric nitrate in Russia

 

[ASheSChem]

After some synthesis, I still have somes questions...

1)

when you wash aluminium with water, we need to wash it until to have a clear water ?
every wash water are more clear, but after 2 or 3 wash it always little grey

ASheSChem
2) when you have put the P2NP solution, the video says we need to wait stop bubbling...
but after loong time he continue to doing very little bubble... and I have the impression that when I wait too long, my yielding is worse in the end
so can we stop when it do little bubbles ?

 

[danil1398]

Can ethanol 96% be used in the process instead of isopropyl 99.8% alcohol

 

[ASheSChem]

nobody ?
@Pennywise @G.Patton @DocX @HIGGS BOSSON @HEISENBERG

After some synthesis, I still have somes questions...

1) when you wash aluminium with water, we need to wash it until to have a clear water ?
every wash water are more clear, but after 2 or 3 wash it always little grey

2) when you have put the P2NP solution, the video says we need to wait stop bubbling...
but after loong time he continue to doing very little bubble... and I have the impression that when I wait too long, my yielding is worse in the end
so can we stop when it do little bubbles ?

ASheSChem

 

[G.Patton]

but after 2 or 3 wash it always little gre

ASheSChemIt's okay

2) when you have put the P2NP solution, the video says we need to wait stop bubbling...
but after loong time he continue to doing very little bubble... and I have the impression that when I wait too long, my yielding is worse in the end
so can we stop when it do little bubbles ?

You have to wait end of this reaction and stop bubbling. Also, you can heat reaction mass ~30-60 min at 50 deg to improve yield.

 

[Saul]

Can ethanol 96% be used in the process instead of isopropyl 99.8% alcohol

danil1398
yes

the reason they use isopropyl is becouse it is legal worldwide

 

[cyb3r0]

Is room temperature a reason for the success of the synthesis? What is the appropriate degree for that?

 

[danil1398]

Tnx for answers. I have a few more questions.

After amalgamation and washing with the addition of P2NP, a rapid violent reaction occurred. After that it became a rare gray liquid in which mercury began to appear.
Is it due to poor preparation of mercury nitrate. Whether there may have been too much mercury.

Please clarify the preparation of mercury nitrate.
Mercuric and nitric acid. How long should be heated to 60 degrees.

 

[danil1398]

We made poultry nitrate according to video instructions here on the forum, but somewhere we read here on the forum that nitrogen acid and mercury must be warmed at 60 C because only then a live nitrate is created.

1. Can I save the rest of the living nitrate I do not use for synthesis? If yes, what should be stored in? What shelf life does a live nitrate have so prepared?
2. If aluminum shampoos, Laboratorska aluminum granules were used for synthesis, would it be better or worse than foil? Can be tiring to cut pieces of 1.5cmx1,5cm
3. Time of completion of amalgam aluminum; When 1l of distilled water is placed in the flask, live nitrate and aluminum foil in pieces - the synthesis says for 10-15 min while dark is color and small bubbles, I think of that part. The question is what if it stays for too long, say 30 minutes, what are the postures of it?
4. There is someone a concrete, accurate and reliable link to buy live nitrate in the EU but send private customers and not companies? Or do you have any of you here for the sale of living nitrate?

 

[MadHatter]

If you use dilute nitric acid, the wrong kind of mercury salt can be synthesised (mercury(I)nitrate instead of mercury(III)nitrate). use concentrated nitric acid.

 

[MadHatter]

Also, when you rinse the amalgam, don't pour the rinsing water down the drain. it's poison. Also, if toxic substances are detected in the water treatment plant, they can trace the area where it's from. Potentially problematic. Convert the mercury salt to harmless mercury sulfide first: http://bbzzzsvqcrqtki6umym6itiixfhn...nion/threads/neutralizing-mercury-salts.2482/

 

[malayboy]

If you use dilute nitric acid, the wrong kind of mercury salt can be synthesised (mercury(I)nitrate instead of mercury(III)nitrate). use concentrated nitric acid.

DocXbut if we use the correct mol in the mercury nitrate equation, even 50% nitric acid can treated as concentrated with correct mol synthesis, yes?

Hg + 4HNO3 ----> Hg(NO3)2 + 2NO2 + 2H2O,

 

[malayboy]

@ASheSChem

hi i face the same problem with you, but I wash with cold tap water, are you washing it with cold distilled water?

 

[Mclssmxxl]

We made poultry nitrate according to video instructions here on the forum, but somewhere we read here on the forum that nitrogen acid and mercury must be warmed at 60 C because only then a live nitrate is created.

1. Can I save the rest of the living nitrate I do not use for synthesis? If yes, what should be stored in? What shelf life does a live nitrate have so prepared?
2. If aluminum shampoos, Laboratorska aluminum granules were used for synthesis, would it be better or worse than foil? Can be tiring to cut pieces of 1.5cmx1,5cm
3. Time of completion of amalgam aluminum; When 1l of distilled water is placed in the flask, live nitrate and aluminum foil in pieces - the synthesis says for 10-15 min while dark is color and small bubbles, I think of that part. The question is what if it stays for too long, say 30 minutes, what are the postures of it?
4. There is someone a concrete, accurate and reliable link to buy live nitrate in the EU but send private customers and not companies? Or do you have any of you here for the sale of living nitrate?

danil13982.Use foil, granules is too reactive.With foil put in coffee grinder or form by hand loose balls.Thin squares are too reactive, it will foam and potentially escape the flask or release vapors.
3.You can leave it too long aswell as too short.The better case is too long but ideally you wanna use as it’s just ready: most aluminium to the top, not too intense bubbling, gray precipitate, drain and use.
4.onyxmet used to have, not in stock now but worth checking.You can also look on olx.pl, allegro.pl.Google translate to polish the chemical name.

 

[G.Patton]

1. Can I save the rest of the living nitrate I do not use for synthesis? If yes, what should be stored in? What shelf life does a live nitrate have so prepared?

danil1398You can store it in a tightly closed dark flask in fridge undetermined long time