Whats the most interesting Drug no one talks about ?

[ps1ch0pth]

Hi,
im just curious, whats the most interesting Drug no one talks about, that deserves more attention ? And why do you think the drug gets that little attention ?

Thanks
Ps. Sorry for my bad english its not my native language

 

[Gordon Ramsay]

There are many new drugs that could replace the most common drugs like Cocaine, MDMA, Amphetamine but global drug users are used to the basic drugs and do not trust into new substances

 

[UWe9o12jkied91d]

4-MAR looks spooky but could be tried, who knows.
Fluorococaine is another interesting one.

 

[BevItUp]

4-MAR looks spooky but could be tried, who knows.
Fluorococaine is another interesting one.

UWe9o12jkied91dI'm kinda wondering about the 4-MAR as well.

I'd like to hear a narrative from someone who's used to taking stimulants, because the accounts online are all over the place, and most of them seem made up.

All I know for sure is it lasts at least 16 hours if you take orally.

 

[scoobiedoo]

I'm kinda wondering about the 4-MAR as well.

I'd like to hear a narrative from someone who's used to taking stimulants, because the accounts online are all over the place, and most of them seem made up.

All I know for sure is it lasts at least 16 hours if you take orally.

BevItUpAfew years ago I tried to find a vendor or manufacturer of 4-MAR and couldnt find anyone who knew where to get it or had even heard of it before. China let me down,again. it sounds good but you never know.

 

[Curious Learner]

4-MAR looks spooky but could be tried, who knows.
Fluorococaine is another interesting one.

UWe9o12jkied91d4’-Fluorococaine? Where does one find this?

 

[thelifeofri1ey]

DMT! The spirit molecule - for suuureeee!
If you give 20 people a spliff, some will get paranoid & some will get starving hungry, some will freak out, some will socialise more, some less; give 20 people a decent dose of DMT & everyone has the same general experience... Not to mention it's naturally occurring EVERYWHERE!

 

[Antihero999]

KU crystal

 

[HIGGS BOSSON]

In my opinion, BK-MDMA deserves special attention.

 

[the right stuff]

2ct2

 

[amieri]

2ct2

the right stuffThat and 2ct7 ,the 2c's in general too

 

[testint]

That and 2ct7 ,the 2c's in general too

amieriGive me a 2c-21
2c-n the infamous 2-CP

 

[testint]

Give me a 2c-21
2c-n the infamous 2-CP

testint2cp was as bad as 2cn but 2c21 was a gem

 

[hermano]

sex with woman

 

[Gordon Ramsay]

sex with woman

hermanoWas about to say that

 

[Dr.Mirakulix]

@BevItUp
@UWe9o12jkied91d

Sadly both the original Aminorex and it's RC derivatives (4,4-DMAR, 4-MAR and it's 4-halogenated versions) are notorious for being responsible for many deaths even among casual users. Especially repeated and prolonged use seems to be dangerous. This isn't some kind of "maybe" danger, it is definitely known to cause severe lung complications that more often than not are fatal.

I cite a reddit comment about this:

4-Methylaminorex, like aminorex, seems to cause pulmonary arterial hypertension (PAH). Aminorex was a prescription drug that got pulled from the market two years after its introduction because of this. The aminorex-related cases of PAH were often severe: half of patients with aminorex-related PAH were dead within 10 years from heart failure.

This is both the reason for MAR's removal from the market as a pharmaceutical and also why none of it's analogues became RC shootingstars like many other cathinones or amphetamines, although it was said to have partly superior effects to them.

Sources:
Here is an article about 4,4-DMAR
Reddit link to a thread about 4-MAR

I throw another substance into the ring that funny enough is made from the same precursor as 4-MAR:

Phenmetrazine

It is said to be a clean, very euphoric upper. This whole class of stimulant drugs is often overlooked and somehow got forgotten.

 

[Unclejoe007]

@BevItUp
@UWe9o12jkied91d

Sadly both the original Aminorex and it's RC derivatives (4,4-DMAR, 4-MAR and it's 4-halogenated versions) are notorious for being responsible for many deaths even among casual users. Especially repeated and prolonged use seems to be dangerous. This isn't some kind of "maybe" danger, it is definitely known to cause severe lung complications that more often than not are fatal.

I cite a reddit comment about this:

4-Methylaminorex, like aminorex, seems to cause pulmonary arterial hypertension (PAH). Aminorex was a prescription drug that got pulled from the market two years after its introduction because of this. The aminorex-related cases of PAH were often severe: half of patients with aminorex-related PAH were dead within 10 years from heart failure.

This is both the reason for MAR's removal from the market as a pharmaceutical and also why none of it's analogues became RC shootingstars like many other cathinones or amphetamines, although it was said to have partly superior effects to them.

Sources:
Here is an article about 4,4-DMAR
Reddit link to a thread about 4-MAR

I throw another substance into the ring that funny enough is made from the same precursor as 4-MAR:

Phenmetrazine

It is said to be a clean, very euphoric upper. This whole class of stimulant drugs is often overlooked and somehow got forgotten.

Dr.MirakulixAminorex analogs I agree. I think cyanogen bromide or cyanate salts used has a lot to do with there synthesis not being persued more.

 

[OrgUnikum]

@BevItUp
@UWe9o12jkied91d

Sadly both the original Aminorex and it's RC derivatives (4,4-DMAR, 4-MAR and it's 4-halogenated versions) are notorious for being responsible for many deaths even among casual users. Especially repeated and prolonged use seems to be dangerous. This isn't some kind of "maybe" danger, it is definitely known to cause severe lung complications that more often than not are fatal.

I cite a reddit comment about this:

4-Methylaminorex, like aminorex, seems to cause pulmonary arterial hypertension (PAH). Aminorex was a prescription drug that got pulled from the market two years after its introduction because of this. The aminorex-related cases of PAH were often severe: half of patients with aminorex-related PAH were dead within 10 years from heart failure.

This is both the reason for MAR's removal from the market as a pharmaceutical and also why none of it's analogues became RC shootingstars like many other cathinones or amphetamines, although it was said to have partly superior effects to them.

Sources:
Here is an article about 4,4-DMAR
Reddit link to a thread about 4-MAR

I throw another substance into the ring that funny enough is made from the same precursor as 4-MAR:

Phenmetrazine

It is said to be a clean, very euphoric upper. This whole class of stimulant drugs is often overlooked and somehow got forgotten.

Dr.MirakulixThe authors of the article which tried to explain the mechanism by which Aminorex and Phentermine cause PAH - by affinity to a certain HT5 serotonine rezeptor which affects the heart - have meanwhile stated that they meanwhile found out Aminorex does not do this, and now no explanation exists how this should happen. (Phentermine though is still a bad one). Aminorex does also not cause PAH in animals and seemingly also not in the USA as the trials there with some 2000 participants which had taken place before those in Europe had found nothing like it. 4-MAR seems to have caused PAH in one group of Americans producing it - if one trusts anecdotal evidence lanced by the DEA.
Also the number of people who got PAH was 2%% (promille, 2 from 1000) whats pretty much the statistically number which was to be expected.
PAH is also cumulative, say when it starts it is self-re-enforcing and nowadays we have medication which stops it when it starts - Viagra and Cialis, the whole group of medication was developed to treat PAH, the other positive effects were just a coiincidence. In short: 5 mg Tadalafil per day keeps PAH away (and provides better circulation to the nether regions as side-effect).

But I do not claim to know for 100% or that I can prove the whole PAH story is bogus. Not yet at least. I would recommend to take Cialis or Viagra in small daily doses when consuming anything from this family and I would include Morpholines like Phenmetrazine just to make sure. I actually would recommend to do this anyways if you are beyond 35 or so.

The reason why 4-MAR vanished is IMHO that it is a VERY long acting drug but not nearly as euphoric and activating as Crystal Meth and Tweakers want to tweak not just be wide awake. 4-MAR simply does not live up to the hype, similar to most RCs which usually pale when compared with plain Amphetamine or 2c-B or MDMA not to talk of LSD.

 

[oldgalaxy]

Idk If nobody talks about it but not really mainstream but many gabapentinoids are really nice like phenibut, pregabalin

 

[Gordon Ramsay]

Idk If nobody talks about it but not really mainstream but many gabapentinoids are really nice like phenibut, pregabalin

oldgalaxyYeah Pregabalin is getting more and more common!

 

[idlewild]

I've never had it but memantine is definitely on my bucket list. Dissociative and it lowers amphetamine tolerance? Sign me up

 

[BevItUp]

I've never had it but memantine is definitely on my bucket list. Dissociative and it lowers amphetamine tolerance? Sign me up

idlewildI have read about this one as well.

I guess if you ever get Alzheimer's you'll be in luck because they will pump you full of it!

 

[idlewild]

Lol yeah that's what I was thinking until my psychiatrist brought it up randomly one visit. I about shit my pants but she nothing came of it

 

[middlemaneu]

[reply related to OP]

5-(1-methylpropyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
or, in one way simpler word: Talbutal - or possible WW legal status analogues of this specific one - non-toxic, non-mutagenic or any other dangerous properties.

 

[Frit Buchner]

Harmaline. Most people think it is just an MAOI A, but it's a hallucinogen. I took 200mg the other day and had auditory and visual hallucinations. What is interesting is that the visuals were quite different from tryptamines I have tried like N,N,DMT, psilocin or LSD. Honestly not as profound but not at all similar. No geometric shapes or purple and greens.. also no coordination and heavy inebriation. I got it off of Ebay

 

[Mr Gonzo]

Harmaline. Most people think it is just an MAOI A, but it's a hallucinogen. I took 200mg the other day and had auditory and visual hallucinations. What is interesting is that the visuals were quite different from tryptamines I have tried like N,N,DMT, psilocin or LSD. Honestly not as profound but not at all similar. No geometric shapes or purple and greens.. also no coordination and heavy inebriation. I got it off of Ebay

Frit BuchnerThat I did not know, I have started growing a load of Syrian Rue. Will have to try this one out!