L-Efedrin-syntes från L-fenylacetylkarbinol (L-PAC)

[OrgUnikum]

l-PAC-trådar blir alltid omedelbart överkörda av skitsnackare, så jag säger adjö.

Du fick den viktigaste informationen: Acetaldehyd eller pyruvat, en lämplig jäst och ph <5.

Ingen ställde den stora och uppenbara frågan: Hur kan jag ta reda på om en jäststam är bra eller inte?
Och eftersom ingen frågade kommer det inte att finnas något svar utan bara att nämna att det finns ganska enkla metoder.
Lycklig sökning, PM inte mig.

Hej då

 

[handle]

Hur kan jag ta reda på om en jäststam är bra eller inte?

 

[handle]

Saccharomyces cerevisiae (Baker’s Yeast)

 

[bilibili]

L-PAC and solvent, add methylamine gas into the mixture, no reaction after 10 hours at room temperature. Does the reaction require heating?

 

[bilibili]

The amount of methylamine gas is too small and has not come into contact with the PAC. Ignore this issue.

 

[rampage]

hey bro can you share your method of producing the l-pac, i have what i believe should be 10mls of pac in solvent but have not yet distilled to remove the solvent, so am not yet sure if i have anything.

 

[bilibili]

Using modified engineered bacteria, much better than yeast.

 

[rampage]

okay is that like e,coli

 

[bilibili]

Yes

 

[bilibili]

Having received the product, now preparing to test whether the structure is racemic.

 

[bilibili]

The resulting of L-Ephedrine Hydrochloride has a purity> 98%, matching exactly that of the L-PAC, no racemization occurred.
The entire synthetic process has been successful.

 

[rampage]

excellent job mate, whats the chances of getting you to post your procedure for the production of l-pac using e,coli and then to ephedrine??

 

[bilibili]

If you're interested, just PM.

 

[MadRick]

Please post your procedure bilibili!

 

[bilibili]

The product is racemic after reduction with NaBH4, need to use catalyst/H2.