• The BB team is looking for employees, who are ready to work with mephedrone, amphetamine, methamphetamine and other substances.
    High wage! Stable job.

    Requirements:

    • Make a minimum deposit of 50 EUR
    • Receive a batch of goods (from 25 g and more, depending on the deposit)
    • Pack the goods in bags (1-2g) and hide them in safe places in your city.

    We going to do the rest work! As soon as the goods are sold, you'll get money for each successfully sold package!

    Relevant for all EU countries and UK

    Contact : @Madre

Joined
Jul 25, 2021
Messages
193
Reaction score
269
Points
63
DnzLBhvNV1
Methylone (3,4-Methylenedioxymethcathinone, βk-MDMA) is a synthetic substance of the cathinone class that is often compared to MDMA. This product is very popular and causes a strong euphoria and empathy. It acts as a powerful aphrodisiac, the effect of which causes an unrestrained desire to have sex.
LvPtWE6U08
This article describes the synthesis of a small amount of methylone. I would like to note that the reaction scales linearly and the proportions of all substances are maintained. Methylone is quite easy to produce in large quantities. Its production does not require sophisticated laboratory equipment. This article describes the technology for producing methylone from halogen ketone (2-bromo-3,4-methylenedioxypropiophenone), which is obtained by standard bromination from 3,4-methylenedioxypropiophenone (3,4-(methylenedioxy)phenyl-1-propanone (MDP1P)).

Reagents:
  • 3,4-Methylenedioxypropiophenone (MDP1P; cas 28281-49-4) 20 g;
  • Dichloromethane (DСM) 90 ml;
  • Bromine (Br2) 22 g;
  • Sodium thiosulfate (Na2S2O3) aq solution 10% ~50 ml;
  • Distilled water;
  • n-Methylpyrrolidone (cas 872-50-4) 50 ml;
  • Methylamine aqueous 40% 20 ml;
  • Sodium bicarbonate 12 g;
  • Magnesium sulphate (MgSO4) ~30 g;
  • Hydrochloric acid (~35%) ~10 ml;
  • Acetone;
Equipment and glassware:
  • Flat bottom flask 250 ml;
  • Retort stand and clamp for securing apparatus (optional);
  • Magnetic stirrer;
  • Reflux condenser (optional);
  • Funnel;
  • Syringe or Pasteur pipette;
  • pH indicator papers;
  • Beakers (500 mL x1, 250 mL x2; 100 mL x2);
  • Vacuum source;
  • Laboratory scale (0.1-200 g is suitable);
  • Measuring cylinders 100 mL;
  • Cold water bath;
  • Glass rod and spatula;
  • Separatory funnel 1 L (optional);
  • Laboratory grade thermometer;
  • Buchner flask and funnel;
  • Filter paper;
Synthesis procedures
MDP1P 20 g is dissolved in DСM 60 ml and a few drops of hydrochloric acid are added, then bromine 22 g is added dropwise. The reaction is exothermic, the reaction mixture is become dark, then become light by reason of hydrobromide (white gas) releasing. The remaining bromine is removed with 10% sodium thiosulfate aq solution and reaction mixture is washed with water after the end of this reaction. The organic layer can be used for the methylamination reaction (yield ~140% MDP1P) or distill off DСM under vacuum to a solid.

The synthesis is conducted under normal conditions. 2-Bromo-3,4-methylenedioxypropiophenone 10 g from previous step is dissolved with n-methylpyrrolidone 50 ml in the reaction flask. The mixture is stirred until solids are dissolved.
XcuQHTMzkp
Methylamine aqueous 40% 20 ml is added to the mixture, the flask is closed and stirred vigorously. Exothermic reaction have to be controlled. The reaction ends in 10 min and temperature decrease.

The exothermic reaction can be very violent and a forced cooling is necessary in case of large load. The flask should be immersed into a cold water bath for cooling. It is important to keep the temperature below 55 ºC.
QVTqOU6mR3
Methylone free base purification
The reaction mass is washed with sodium bicarbonate solution after reaction end, which is prepared in advance (water 120 ml and sodium bicarbonate 12 g). Sodium bicarbonate solution is poured into the reaction mixture and stirred vigorously for 1-2 min.
Cn5pETB1OI
Dichloromethane (CH2Cl2) 30 ml is added and stirred vigorously for 5 min. Methylone free base is extracted by DCM from this mixture. Organic layer is separated with help of separatory funnel.
CYFu1wPcRQ
Extraction
Layers separation in separating funnel (Photo 1). The bottom layer is DCM extract with cathinone base. The aqueous fraction is top layer, which have to be separated and extracted one more time with DCM 30 ml (Photos 2-3-4). The lower organic layers are combined and washed with distilled water 60 ml 3-4 times in separatory funnel until the methylamine smell absent (Photo 5-6). Methylone free base in DCM is always in the bottom layer. Layers are separated carefully. Try to avoid getting water into the organic layer. Organic solution is dried over MgSO4.
Ilo54CD2dg
Acidification
Methylone free base solution in DCM is diluted with an equal volume of dry acetone (Laboratory grade 99%+). Then hydrochloric acid (~35%) is added in small portions dropwise. The mixture is stirred constantly and pH is controlled. A precipitate is appeared. If the mixture became very thick, acetone is added.
9Pb2tE4KvY
The mixture must be very liquid in order to acidify methylone properly. When pH is reached 5.5-6, HCl addition is stopped. The mixture is cooled and filtered.
IZ8e71PmBb
If methylone hydrochloride is not pure enough, you can read how to purify it here. Large crystals producing is described in this article.

Methylone hydrochloride purification with dry acetone gives a good result. There are several pictures of methylone hydrochloride before and after purification procedure.
VyerkFfsCY

ELiAWq8a9r
 
Last edited by a moderator:

BHBlueberry

Don't buy from me
New Member
Joined
Jan 17, 2022
Messages
20
Reaction score
9
Points
3
good M1 have a great blow - for me even too great to produce it :) You use a lot of DCM here, I don't like it, can I replace it with anything else? (Ether?)
 

karamelosanto

Don't buy from me
New Member
Joined
Apr 14, 2022
Messages
15
Reaction score
4
Points
3
HI, Thanks for sharing this synthesis, I think is very clear.
I am from South America and here is a little difficult to find DCM. However, I can try to find it in some way. Maybe buying it from china.
I want to ask. Can you put all the regents in a list with quantities to make a little more easy to understand what I must to buy. If is possible with an estimated price.
Thanks!!!
 
Joined
Jul 25, 2021
Messages
193
Reaction score
269
Points
63
HI, Thanks for sharing this synthesis, I think is very clear.
I am from South America and here is a little difficult to find DCM. However, I can try to find it in some way. Maybe buying it from china.
I want to ask. Can you put all the regents in a list with quantities to make a little more easy to understand what I must to buy. If is possible with an estimated price.
Thanks!!!
karamelosantoDCM can be replaced by a more readily available solvent. The quantities of reagents depend on your needs.
I wrote to you on the PM for a more detailed discussion.
 

Jacka

Don't buy from me
New Member
Joined
Apr 27, 2022
Messages
5
Reaction score
0
Points
1
can mytalamine 40% be replaced?
 
Joined
Jul 25, 2021
Messages
193
Reaction score
269
Points
63
Methylamine cann't be substituted. If you have a lower % of methylamine, you can use it.
You can use methylamine hydrochloride instead of methylamine solution, but an alkaline solution must be added.
 
Last edited by a moderator:

antrax

Don't buy from me
Resident
Joined
May 14, 2023
Messages
163
Reaction score
54
Points
28
Methylamine cann't be substituted. If you have a lower % of methylamine, you can use it.
You can use methylamine hydrochloride instead of methylamine solution, but an alkaline solution must be added.
Marvin Popcorn SuttonMy friend, could you tell me the color and texture in it´s pure and impure state of the synthetic cathinone precursor 2-Bromo-3',4'-(methylenedioxy)propiophenone (CAS:52190-28-0)?
Most of the Chinese chemical suppliers sell it in the form of powder and small sandy brown rocks, I don't know if it has that brown color due to impurities or if it is a different chemical, since the supplier told me that said chemical precursor it has a purity of 99% even having that brown color.
thank you!!
 

ASheSChem

Don't buy from me
Resident
Joined
Apr 10, 2022
Messages
287
Reaction score
143
Points
43
possible to find in europe 3,4-methylenedioxypropiophenone or 2-bromo-3,4-methylenedioxypropiophenone ?
 

Jacka

Don't buy from me
New Member
Joined
Apr 27, 2022
Messages
5
Reaction score
0
Points
1
Methylamine cann't be substituted. If you have a lower % of methylamine, you can use it.
You can use methylamine hydrochloride instead of methylamine solution, but an alkaline solution must be added.
Marvin Popcorn SuttonAnd what alkaline solution should you combine to replace the 20ml of methylamine 40% with methylamine hydrochloride + alkaline solution that you explain in your synthesis
 

Jacka

Don't buy from me
New Member
Joined
Apr 27, 2022
Messages
5
Reaction score
0
Points
1
Can you specify the laboratory instruments that have been used in this process and the use that I play, please :)
 
Joined
Jul 25, 2021
Messages
193
Reaction score
269
Points
63
And what alkaline solution should you combine to replace the 20ml of methylamine 40% with methylamine hydrochloride + alkaline solution that you explain in your synthesis
JackaThe table shows the density of 40% methylamine as 0.89g/ cm3, hence 7.18g of pure methylamine gas is obtained in 20ml.
Let us compare the molecular weights of methylamine and its hydrochloride:
M (CH3NH2)HCl = 67.518 g/mol
M CH3NH2 = 31.057 g/mol.
Ratio = 2.174
If you use the proportions from the synthesis, you will need 15.6g of methylamine hydrochloride to replace 20ml of 40% methylamine solution.
Methylamine hydrochloride needs to be dissolved beforehand in the proportion of 1g to 2.5ml water (15.6g and 39ml).
Prepare sodium hydroxide (NaOH) solution of 18g and 54ml water, let it cool and pour it into a flask with 2-bromo-3,4-methylenedioxypropiophenone solution. After that, add methylamine hydrochloride solution. Then continue according to the instructions.
 
Last edited by a moderator:

Acidosis

Buying through escrow
New seller
Joined
May 31, 2022
Messages
182
Reaction score
117
Points
43
bk-MDMA FROM THIS METHODOLOGY AND home adaptations.
5l6eTjRPuq
 

Attachments

  • BTqb9ONzUv.mp4
    5 MB · Views: 0

darkblink

Don't buy from me
Member
Joined
Jun 2, 2022
Messages
5
Reaction score
0
Points
1
Can DCM be substituted with another solvent? How do i puchase DCM in the UK? I have Xylene and Ethyl Acetate easy available in large quantities to me
 

Acidosis

Buying through escrow
New seller
Joined
May 31, 2022
Messages
182
Reaction score
117
Points
43
ethyl acetate
Can DCM be substituted with another solvent? How do i puchase DCM in the UK? I have Xylene and Ethyl Acetate easy available in large quantities to me
darkblink
 

Mr.Blanks00

Don't buy from me
Resident
Joined
Sep 2, 2022
Messages
43
Reaction score
17
Points
8
hi, sorry friend, I want to ask, how many mg is used when used, this is used by snorting like meth or by swallowing it like a pill. Sorry, I just heard about this new thing.
 

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,388
Solutions
3
Reaction score
2,327
Points
113
Deals
1
hi, sorry friend, I want to ask, how many mg is used when used, this is used by snorting like meth or by swallowing it like a pill. Sorry, I just heard about this new thing.
YusufOral way of administration
Light 75 - 150 mg
Common 150 - 225 mg
Strong 225 - 325 mg
Heavy 325 mg +
 

StarWars

Don't buy from me
New Member
Joined
Dec 7, 2022
Messages
132
Reaction score
67
Points
28
Oral way of administration
Light 75 - 150 mg
Common 150 - 225 mg
Strong 225 - 325 mg
Heavy 325 mg +
G.PattonIm can use dcm like NMP and how much need mix if on NMP need mix only 10 min then how long need mix on dcm ??
 
View previous replies…

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,388
Solutions
3
Reaction score
2,327
Points
113
Deals
1
Is 20 minutes too short for animations?
hexenDo you understand that 10g of substance can react faster than 10 kg? There is difference and reaction time isn't constant. I have no dependence data for this (reaction load : time) reaction. As I told in previous message, you have to control it by TLC.
 

Didi

Don't buy from me
New Member
Joined
Nov 13, 2022
Messages
31
Reaction score
17
Points
8
How to made methyloamine 40% step by step ??
 

Zetetic

Don't buy from me
New Member
Joined
Dec 2, 2022
Messages
18
Reaction score
4
Points
3
Methylone (3,4-Methylenedioxymethcathinone, βk-MDMA) is a synthetic substance of the cathinone class that is often compared to MDMA. This product is very popular and causes a strong euphoria and empathy. It acts as a powerful aphrodisiac, the effect of which causes an unrestrained desire to have sex.
This article describes the synthesis of a small amount of methylone. I would like to note that the reaction scales linearly and the proportions of all substances are maintained. Methylone is quite easy to produce in large quantities. Its production does not require sophisticated laboratory equipment. This article describes the technology for producing methylone from halogen ketone (2-bromo-3,4-methylenedioxypropiophenone), which is obtained by standard bromination from 3,4-methylenedioxypropiophenone (3,4-(methylenedioxy)phenyl-1-propanone (MDP1P)).

Reagents:
  • 3,4-Methylenedioxypropiophenone (MDP1P; cas 28281-49-4) 20 g;
  • Dichloromethane (DСM) 90 ml;
  • Bromine (Br2) 22 g;
  • Sodium thiosulfate (Na2S2O3) aq solution 10% ~50 ml;
  • Distilled water;
  • n-Methylpyrrolidone (cas 872-50-4) 50 ml;
  • Methylamine aqueous 40% 20 ml;
  • Sodium bicarbonate 12 g;
  • Magnesium sulphate (MgSO4) ~30 g;
  • Hydrochloric acid (~35%) ~10 ml;
  • Acetone;
Equipment and glassware:
  • Flat bottom flask 250 ml;
  • Retort stand and clamp for securing apparatus (optional);
  • Magnetic stirrer;
  • Reflux condenser (optional);
  • Funnel;
  • Syringe or Pasteur pipette;
  • pH indicator papers;
  • Beakers (500 mL x1, 250 mL x2; 100 mL x2);
  • Vacuum source;
  • Laboratory scale (0.1-200 g is suitable);
  • Measuring cylinders 100 mL;
  • Cold water bath;
  • Glass rod and spatula;
  • Separatory funnel 1 L (optional);
  • Laboratory grade thermometer;
  • Buchner flask and funnel;
  • Filter paper;
Synthesis procedures
MDP1P 20 g is dissolved in DСM 60 ml and a few drops of hydrochloric acid are added, then bromine 22 g is added dropwise. The reaction is exothermic, the reaction mixture is become dark, then become light by reason of hydrobromide (white gas) releasing. The remaining bromine is removed with 10% sodium thiosulfate aq solution and reaction mixture is washed with water after the end of this reaction. The organic layer can be used for the methylamination reaction (yield ~140% MDP1P) or distill off DСM under vacuum to a solid.

The synthesis is conducted under normal conditions. 2-Bromo-3,4-methylenedioxypropiophenone 10 g from previous step is dissolved with n-methylpyrrolidone 50 ml in the reaction flask. The mixture is stirred until solids are dissolved.
Methylamine aqueous 40% 20 ml is added to the mixture, the flask is closed and stirred vigorously. Exothermic reaction have to be controlled. The reaction ends in 10 min and temperature decrease.

The exothermic reaction can be very violent and a forced cooling is necessary in case of large load. The flask should be immersed into a cold water bath for cooling. It is important to keep the temperature below 55 ºC.
Methylone free base purification
The reaction mass is washed with sodium bicarbonate solution after reaction end, which is prepared in advance (water 120 ml and sodium bicarbonate 12 g). Sodium bicarbonate solution is poured into the reaction mixture and stirred vigorously for 1-2 min.
Dichloromethane (CH2Cl2) 30 ml is added and stirred vigorously for 5 min. Methylone free base is extracted by DCM from this mixture. Organic layer is separated with help of separatory funnel.
Extraction
Layers separation in separating funnel (Photo 1). The bottom layer is DCM extract with cathinone base. The aqueous fraction is top layer, which have to be separated and extracted one more time with DCM 30 ml (Photos 2-3-4). The lower organic layers are combined and washed with distilled water 60 ml 3-4 times in separatory funnel until the methylamine smell absent (Photo 5-6). Methylone free base in DCM is always in the bottom layer. Layers are separated carefully. Try to avoid getting water into the organic layer. Organic solution is dried over MgSO4.
Acidification
Methylone free base solution in DCM is diluted with an equal volume of dry acetone (Laboratory grade 99%+). Then hydrochloric acid (~35%) is added in small portions dropwise. The mixture is stirred constantly and pH is controlled. A precipitate is appeared. If the mixture became very thick, acetone is added.
The mixture must be very liquid in order to acidify methylone properly. When pH is reached 5.5-6, HCl addition is stopped. The mixture is cooled and filtered.
If methylone hydrochloride is not pure enough, you can read how to purify it here. Large crystals producing is described in this article.

Methylone hydrochloride purification with dry acetone gives a good result. There are several pictures of methylone hydrochloride before and after purification procedure.
Marvin Popcorn SuttonGreetings you and to all! Someone can suggest the result and describe the effect of the substance if 3,4-(Methylenedioxy)propiophenone is replaced in this synthesis by 3,4-(Methylenedioxy)butyrophenone.
I had such a question because I found only 3,4-(Methylenedioxy)butyrophenone in our free market.
 

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,388
Solutions
3
Reaction score
2,327
Points
113
Deals
1
Greetings you and to all! Someone can suggest the result and describe the effect of the substance if 3,4-(Methylenedioxy)propiophenone is replaced in this synthesis by 3,4-(Methylenedioxy)butyrophenone.
I had such a question because I found only 3,4-(Methylenedioxy)butyrophenone in our free market.
ZeteticYou'll get 2-Methylamino-1-(3',4'-methylenedioxyphenyl)butan-1-one hydrochloride cas 17762-90-2
 
  • Free product samples

    Testing products from new vendors and manufacturers.

    Get free samples for testing now!

  • Always stay in touch with BB forum. Element/Matrix.

    Connect notifications to always stay in touch with the forum!

    Connect

  • The BB Forum team is looking for cooperation:

    • Traffic arbitrage specialists
    • Spammers
    • Advertising agencies
    • Bloggers/Vloggers
    • TOR sites directories
    • Creative people who can create viral content
    • Administrators of Telegram Channels and Groups

      We will pay more for your traffic than our competitors! $0.1 per visitor!!!If you are interested in, write to the administrator.
Top