Best ways to dosing compounds needing to be measured around 1-10 mg per take?

[LiterateGain]

Hey All!

I need help finding the best, hopefully portable, ways to dose a compound around 1-10 mg per dose taken.

Honestly I was looking forward to pressing my own tablets. But I am also a newbie when it comes to that.
Being open for alternative ways, I would love to hear if there are any other good methods, like capsuling or in general other methods.
The most important aspects are to not supersede 10 mg by far per dose and the doses being portable in the smallest possible form.

Coming back to the tablets, are there any good pressing machines being operatable by hand?
Which do you recommend? When it comes to heavier machinery what kind of budget should I invest?


The compound I want to preferably press into tablets is: 2-Fluoro-6-(phenylethynyl)pyridine in the form of a hydrochloride salt
Molecular Weight: 200,23 g/mol (HCL salt 236,69 g/mol),
Purity: around 97%
Molecular Formula: C13H11NF


Possibly being able to press tablets, I want them to be around 6 mm in diameter and 3 mm in height (height does not really matter, diameter preferably not to be larger than 6 mm).
What kind of carrier substance would you recommend using?

What kind of carrier substance would you recommend if I need to measure the doses in another way?

What is some gear, definitely being needed to own to measure compounds active in these ranges (1-10 mg)?


If I have to make a liquid solution, the best way would be using a pipette bottle? What kind of liquid carrier substance could I use in this case? Is water the best choice?

Appreciating all your input, I am keen to reading your comments. Newbie advice is also appreciated a lot!!
Possibly some of you having book recommendations, please feel free to share them!


Wishing you all success in your projects.


Respects,

LiterateGain

 

[cubesquare]

But I am also a newbie when it comes to that.

LiterateGainThere is a comprehensive guide to tableting here: http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/tableting.348/

The most important aspects are to not supersede 10 mg by far per dose

With tableting or capsulation, you add the weight of your active compound and the weight of your excipients, then mix very thouroughly. Use mechanical mixers, blenders, coffee grinders etc and mix for a long time, up to 30 minutes, and your active ingredient will be evenly distributed through the mix. Even if working with something like melatonin where you want a 1mg dose per capsule, the net weight of the contents of a size 3 capsule will be ~160mg/capsule when you use rice flour as your excipient. This means that if you measure out 160mg per capsule, each capsule will have 1mg melatonin. Do the same thing with other substances. Weight of substances can be easily found with DDG.

What kind of carrier substance would you recommend using?

There are comprehensive lists of suitable tableting excipients in the link I posted above.

definitely being needed to own to measure compounds active in these ranges (1-10 mg)?

A milligram scale is needed, but you never measure 1mg, you decide to make 100 tablets, or 100 capsules, and then measure 100mg of your substance. Then look at you excipients, their weight and work out what each tablet to capsule will need, then add 100 x that of each and blend them together.

What kind of liquid carrier substance could I use in this case? Is water the best choice?

That depends on what you are doing with ther liquid. Water, Saline, Alcohol...