Methamphetamine Synthesis from Ephedrine by Using I2 and H3PO2

[ImRegistered]

Would this synthesis work with p2p ?

 

[hacke8]

No, this is only suitable for ephedrine. P2P uses amalgam or other lines.

 

[hacke8]

Yes, there are many ways to choose the BB forum that suits you.

 

[caydiantak]

does this work with pseudo?

 

[hacke8]

Yes, this thread only applies to ephedrine and pseudoephedrine.

 

[Toti]

Hi is there any difference if i use sudoephedrine in this recepe ?
Thank you

 

[Throw-off]

Different ratios for ephedrine and pseudo.

 

[ZMI_AA0B]

Is there any question about the distillation of anhydrous sodium sulfate after drying in Figure 16? After DCM distillation, amphetamine will be separated from DCM

 

[ZMI_AA0B]

Will the distillation of DCM methamphetamine also be carried out together with Figure 17

 

[ZMI_AA0B]

May I ask if the reason why there is no white sediment when introducing hydrogen chloride is because the extract is not dry? Or are there any other reasons that could have caused it

 

[ZMI_AA0B]

How to operate an information expert if you want to

 

[hacke8]

After the reaction is completed, add water to neutralize the acid, then adjust to alkaline PH10+ and extract it with DCM. After extraction, add sodium sulfate to dry (30 minutes to 1 hour) and filter, evaporate DCM (90-110 degrees) at normal pressure, leaving a light yellow liquid (free base of methamphetamine) and filtered after adding petroleum ether. The filtrate passes through the hydrogen chloride gas to obtain the white powder of methamphetamine hydrochloride.

 

[ZMI_AA0B]

Teacher, what I don't understand is that if I use toluene for extraction and sodium sulfate for dry distillation, will toluene be distilled together with amphetamine

 

[ZMI_AA0B]

Teacher, toluene is a non-polar solvent. Does that mean that after toluene is extracted, dried and filtered, hydrogen chloride can be directly introduced

 

[hacke8]

Please carefully check all reagents and all processes for errors.

 

[ZMI_AA0B]

Teacher, may I ask if the subsequent operation is the same if DCM is changed to toluene? Thank you for your guidance, teacher

 

[ZMI_AA0B]

Teacher, is it feasible to replace DCM with toluene without DCM? Is it correct to distill toluene after drying, leaving behind a yellow liquid instead of distilling it all together

 

[hacke8]

Yes, as long as it is a non-polar solvent. You can also put hydrogen chloride gas directly into the dried solvent without distillation.

 

[ZMI_AA0B]

You are the most enthusiastic here. Only you can reply to me. If I succeed, I will definitely thank you

 

[ZMI_AA0B]

Teacher, this is how I operate. Can you help me take a look! After heating and refluxing, I extracted it with toluene and poured it into anhydrous sodium sulfate to dry it. After filtration, I distilled the toluene and left behind amphetamine before introducing hydrogen chloride

 

[ZMI_AA0B]

May I ask which non-polar solvents can be used to extract methamphetamine

 

[hacke8]

Yes, you can use toluene, benzene, xylene, either. They will not be distilled with the solvent because their boiling point is higher than that of the solvent. You can directly enter the hydrogen chloride gas after drying, without affecting it.

 

[ZMI_AA0B]

Excuse me, teacher. After heating and refluxing, first add alkaline solution with a pH value of 10 or above, and then add sodium thiosulfate before extracting with toluene. Can you teach me the next steps? Thank you

 

[hacke8]

You can use petroleum ether, it depends on your own schedule, and the powder recrystallizes into ice. You can refer to the ICE theme.

 

[JJ237]

Can you please show me this ice theme. I still find it difficult to recrystallize my meth powder to ice

 

[ZMI_AA0B]

Is sodium sulfate drying a mixture of toluene extracted from amphetamine and sodium sulfate for sealing