Methamphetamine synthesis from P2P by NaBH4 reduction. Medium-Scale.

[btcboss2022]

Introduction.​

I represent to BB audience Methamphetamine synthesis method of 1-phenyl-2-propanon (P2P) reduction by NaBH4. Following method allows obtaining and large batches of product. The hardest problem of this method is the heat generating during exothermic reaction of imine reduction. Extremely important keep temperature in described frames and keep all reagent and reaction atmosphere dry (use drying tubes with CaCl2). Also, manipulations with NaBH4 is quite dangerous and take a lot of attention because this reagent has toxic effects, reacts with water and alcohols with releasing enormous amount of hydrogen and form the corresponding borate, it may cause an explosion, burns and injuries. You have to use chemical glass, gloves, chemical coat and respirator.​

Equipment and glassware:​

• Ceramic mortar;​
• 2 L (x2), 0.5 L (x2) and 200 ml (x2) beakers;​
• 2 L (x2) and 10 L Erlenmeyer flask;​
• Measuring cylinder for 100 ml;​
• 2 L three-necked round bottom flask with plugs;​
• 2 L round bottom flask with vacuum quickfit or Schlenk flask;​
• 0.5 L Simple dropping funnel with Claisen flask and drying tube or 0.5 L equal pressure dropping funnel;​
• 1 L Separator funnel;​
• 2 L Evaporation flask;​
• Pyrex dish 0.5 L;​
• Magnetic stirrer with heating plate;​
• Retort stand and clamp for securing apparatus;​
• Silicone-oil bath;​
• Icecubes/methanol bath (-10 °C) or Mashed ice with salt (-10 °C);​
• Laboratory scale (1 g-1 kg is suitable);​
• Oven;​
• Laboratory grade thermometer (-20 °C to 200 °C) with three-necked flask adapter;​
• Aspirator;​
• HCl laboratory generator;​
• Drying tube x2;​
• Rotavap machine with water bath;​
• Filter paper.​

Reagents:​

• 138 gram P2P (1 mole) (1-phenyl-2-propanone);​
• 10% Methylamine in Methanol (w/w) - 1000 ml with 100 g MeNH2 (~3 moles);​
• Magnesium Sulfate - 36 g (MgSO4·7H2O, oven dry at 300 °C for 2h MgSO4·1H2O) [For drying MeOH/MeNH2 solution];​
• Silica Gel (3-5 mm balls) - 200 ml (dry at 300 °C/2h, they will darken!) [For absorbing 2 mol H2O during rxn];​
• 15 gram NaBH4 as a reducing agent for the formed (water-free!) imine;​
• 5-7 L distilled water + ~5 L distilled water to filling rotavap machine bath;​
• 1 L Dichloromethane (DCM);​
• 0.5 L Acetone.​

Important: the reaction is very sensitive to any water (fluid or vapour in the air!).

Note: hold all manipulations in pull out probe or under exhaust hood; methylamine is a rather toxic substance, do not let its vapors enter the respiratory tract. Using respiratory mask is required. Inhalation of methylamine causes severe skin irritation, eyes and upper respiratory tract. Firstly, leads to excitement and then to depression of the central nervous system. Death can occur from respiratory arrest.​

Procedure.​

Precursors drying.
First quickly crunch your pre-dried (oven, 300 °C, 3 hrs.) dry MgSO4 to pop corn shaped rocks in a mortar, sieve the powder out, and directly put the rocks under max. mixing in the Methanol/Methylamine mix (1000 ml) and close the pot to let no water from the air in. Keep mixing for 10 minutes, then all the water will be taken up to the MgSO4. Let stand and wait till all the MgSO4 is on the bottom. Now quickly tap off the now dry MeOH/methylamine (MA) mix in a 2 L three-necked round bottom flask and close that one. Wash directly your empty pot with lots of water, to remove the smell of methylamine, so you can safely store it.
​

Synthesis.

Now add the 200 ml (measure in beaker, neglect the free spaces) dry Silicagel beads (2-5 mm) and a magnetic mixer bar also in the 2 L flask and close again. Keep 2 L flask in Silicone-oil bath at 20 °C. Silicone-oil only slowly warms up! Do not apply heat now, it's only meant as a cooling medium in this stage. Now add slowly via a dropping funnel the 138 g P2P to the 2 L flask under strong mixing. The temperature rises to 23 °C during the (water-free) Imine forming. The water from this reaction is taken up by the dried Silicagel! This takes 30 minutes. Let, then mix for another hour. The reaction mix color changes from light yellow to coffee+milk color. Temp 23 °C.​

View attachment 2944 ​

Stop mixing after this 1 hour and pour the fluid off into a 2 L glass erlenmeyer with flat bottom and add a mixbar. The remaining Silicagel is washed 3 times with 50 ml dried (use silicagel) methanol, to catch the remaining Imine, and those 2 x 50 ml is also poured into the 2 L erlenmeyer. Now put the 2 L erlenmeier on magn.mixer, in an icecubes/methanol bath (-10 °C) (or mashed ice with salt) and start strong mixing. Put a drip funnel on top of 2 L erlenmeier, in rubber ring. Now start adding, every 5 min., a teaspoonfull (flat off!) of NaBH4 in minimum methanol, wash it from funnel with minimum methanol amount. After every spoonfull, stopper the funnel loosely with a rubber stopper. This takes 2.5 hrs. Do not exceed a temp of more than 20 °C! You can add the next spoon at ±8 °C. Solution color is light clear orange/brown. Let mix in total for 8.5 h (could perhaps be lot fewer hours).​

View attachment 2945 ​

The total volume is ~1900 ml. Add then the mix to 5 L distilled water into a 10 L flask, under magn.mixing. The pH=12. Add then 500 ml DiChloroMethane (DCM) and mix strongly for 30 min. Let oil precipitate and a dark, honey-coloured layer of DCM+oil settle onto the bottom. Decant the water part with an aspirator + siliconetube. Fill the rest (water+DCM+oil) in a seperatory funnel and tap off only the DCM+oil = 550 ml. (DCM b.p. 40 °C). The leftover MgSO4 and boro salts stayed nicely in the waterpart. Then dry the DCM+oil with some dry MgSO4 and decant in 2l erlenmeier. Wash this MgSO4 with some fresh, DRY DCM and add the DCM washings to the now dry DCM+oil. Total volume DCM+oil =1000 ml, colour is honey/red.​

Producing methamphetamine hydrochloride.

Start now bubbling this 1000 ml with HCl-gas via 2 L Schlenk flask (or round bottom flask with vacuum quickfit), while this 2 L flask stands in ice bath on magn. mixer and blends vigorously. Check pH frequently, proceed until pH 6. Pour the now acidified 1000 ml in a 2 L evaporation flask and put on Rotavap machine. Spee~100 rpm, t° = 80 °C, little vacuum=0.8 bar (water-jet aspirator is enough), to hold the flask. After distillating off nearly all the DCM, suddenly the contents of the flask turns from dark honey colour to creamy milk color, and it dries out to a round cake on the bottom. Remove the ~0.5 L DCM, now in the collector flask, and hang that empty flask on again. Now put full vacuum on to remove the last traces of water.

Cleaning by 3 x recrystallization: put minimum quantity of hot (40 °C) dry DCM (or dry 98%+ ethanol) in the flask until the last remains of the dry stuff dissolves, and add 4x this DCM-quantity in the form of dry acetone. Close with stopper and put 1 hr in freezer. A solid dirty-white crystal mass is formed with a layer of dark red fluid on top of it. Decant the fluid and repeat this step another 2x and 2 hrs. You have, the last time, snow-white crystals of racemic methamphetamine hydrochloride. Dry Weight = 141.5 g, close to quantitative yield.

Methamphetamine purification.
You can use this technique or follow next advices to produce ICE meth: melt this crystal mass in an alu flat bottom pot on a heater plate at 170-175 °C. Then let this melt, very slowly, and do not go higher than necessary to melt it, or its starts smoking (you have your first quick-test then: enjoy!). Cool down to 150 °C again, really slowly, 1 °C/30 min. (regulate with your temp controller!), and you got ICE, after you let it very slowly again cool down to room temperature (with a closed lid on it!, its hygroscopic!). Advantage: you removed all the water in this process!

You can better make the sulfate salt following logical method: Let 10% H2SO4/Ethanol mix acidifying a 1:4 mix of freebase Meth/Ethanol. This is not so hygroscopic. Filter and dry the crystals.​

G.PattonHello,

After many tests using Methylamine HCL based on this method I will share the best way that I found to obtain Methamphetamine freebase in big scale:

• 966 gr P2P​
• 14 liters Methanol
• 1183 gr Methylamine HCL​
• 638gr NaOH​
• 452 gr Anhydrous Sodium Sulfate​
• 105 gr NaBH4​
• 35 L distilled water​
• 7 Liters DCM​

- Fill the reactor with the 14 L of Methanol
- With stirring dissolve the Methylamine HCL
- Put the reactor temp at 0C(not the mixture temp) and add the NaOH, the temp will increase
- Once the temp come back to 20C add the P2P, the temp will increase stir it during 45min-1 hour
- Add 252gr of anhydrous sodium sulfate
- When the mixture temp arrives to 8C start adding portionwise the NaBH4 not exceeding the 20C
- Once all the NaBH4 has been added let it mixing under 20C during aprox 2 hours until the mixture stops bubbling
- Add the water and continue mixing during 5 min
- Add the DCM and mix it during 10 min
- Stop stirring and let layers get separated
- Keep the bottom layer and discard the upper one( not profitable to extract this aqueous phase)
- Add 200gr of anhydrous sodium sulfate to the saved layer and mix it
- Filter it in Buchner Funnel
- Evaporate the DCM
- Clean and smelly Methamphetamine freebase obtained

;-)

 

[ossi]

Hello,

After many tests using Methylamine HCL based on this method I will share the best way that I found to obtain Methamphetamine freebase in big scale:

• 966 gr P2P​
• 14 liters Methanol
• 1183 gr Methylamine HCL​
• 638gr NaOH​
• 452 gr Anhydrous Sodium Sulfate​
• 105 gr NaBH4​
• 35 L distilled water​
• 7 Liters DCM​

- Fill the reactor with the 14 L of Methanol
- With stirring dissolve the Methylamine HCL
- Put the reactor temp at 0C(not the mixture temp) and add the NaOH, the temp will increase
- Once the temp come back to 20C add the P2P, the temp will increase stir it during 45min-1 hour
- Add 252gr of anhydrous sodium sulfate
- When the mixture temp arrives to 8C start adding portionwise the NaBH4 not exceeding the 20C
- Once all the NaBH4 has been added let it mixing under 20C during aprox 2 hours until the mixture stops bubbling
- Add the water and continue mixing during 5 min
- Add the DCM and mix it during 10 min
- Stop stirring and let layers get separated
- Keep the bottom layer and discard the upper one( not profitable to extract this aqueous phase)
- Add 200gr of anhydrous sodium sulfate to the saved layer and mix it
- Filter it in Buchner Funnel
- Evaporate the DCM
- Clean and smelly Methamphetamine freebase obtained

;-)

btcboss2022i have actually Methylamin-Water solution. How to remove water? Water is dangerous in this reaction i think

 

[Hank Schrader]

Chemically speaking, methamphetamine is methamphetamine. No matter what method it is obtained, borohydride or hydrogenation, etc...
But to be honest, NaBH4 methamphetamine is very inferior in terms of time of action and quality.
Perhaps minimal impurities that remain in other production methods and give a specific effect to the product.
In the case of borohydride, the action time is up to 16-18 hours and large dosages of the racemic product.
I think the people who synthesized borohydride methamphetamine would agree with me.
For example, methamphetamine obtained by the leukart method and divided into isomers is effective for almost 2 days.
Received methamphetamine through Sodium borohydride and separated into isomers acts only 16 hours and higher dosage.
The absence of impurities in the base is guaranteed by fractional distillation and division into isomers.
Of course, this sounds very strange, because from a chemical point of view, methamphetamine is methamphetamine, but as practice shows, this is not so.
Using the example of Viagra, I can tell you that fizer is unique in the production of sildenefil, and if you compare it with generics that have a similar amount of active ingredient, you will feel the difference.

 

[Macondor]

Chemically speaking, methamphetamine is methamphetamine. No matter what method it is obtained, borohydride or hydrogenation, etc...
But to be honest, NaBH4 methamphetamine is very inferior in terms of time of action and quality.
Perhaps minimal impurities that remain in other production methods and give a specific effect to the product.
In the case of borohydride, the action time is up to 16-18 hours and large dosages of the racemic product.
I think the people who synthesized borohydride methamphetamine would agree with me.
For example, methamphetamine obtained by the leukart method and divided into isomers is effective for almost 2 days.
Received methamphetamine through Sodium borohydride and separated into isomers acts only 16 hours and higher dosage.
The absence of impurities in the base is guaranteed by fractional distillation and division into isomers.
Of course, this sounds very strange, because from a chemical point of view, methamphetamine is methamphetamine, but as practice shows, this is not so.
Using the example of Viagra, I can tell you that fizer is unique in the production of sildenefil, and if you compare it with generics that have a similar amount of active ingredient, you will feel the difference.

Hank Schraderand in the MDMA case? can i dm to you?

 

[masiuka]

Dear Colleagues.
I've read that some of you purify meth freebase by steam distillation.
I do not have enough efficient vacuum pump to keep water boiling poing below 60 deg.C so I thought I can instead wash it several times with distilled water.
To my surprise...first try of washing created emulsion that didn't want to break.
Eventually I added enough NaCl to create saturated solution and force the separation and I was able to recover freebase...
...anyway...
Can someone explain my how steam distillation can allow to get separated freebase and water layers and mixing it with water just gives my unbreakable emulsion?
I just don't get it. What's a difference??

 

[w2x3f5]

Dear Colleagues.
I've read that some of you purify meth freebase by steam distillation.
I do not have enough efficient vacuum pump to keep water boiling poing below 60 deg.C so I thought I can instead wash it several times with distilled water.
To my surprise...first try of washing created emulsion that didn't want to break.
Eventually I added enough NaCl to create saturated solution and force the separation and I was able to recover freebase...
...anyway...
Can someone explain my how steam distillation can allow to get separated freebase and water layers and mixing it with water just gives my unbreakable emulsion?
I just don't get it. What's a difference??

masiukaUse the solvent for extraction, dichloromethane, as an example.

 

[masiuka]

Use the solvent for extraction, dichloromethane, as an example.

w2x3f5I see I did bad assumption thinking that steam distilled freebase will separate from water itself :-/
I combined the brine I had left with NaOH from reaction slury extract and I extracted it with IPA getting a little more of freebase.
The puny amount, I think, but, as Albert Hoffman said (starting his work in Sandoz), we need to learn working with small amount of chemicals ;-)

Thank you for quick advice

 

[w2x3f5]

I see I did bad assumption thinking that steam distilled freebase will separate from water itself :-/
I combined the brine I had left with NaOH from reaction slury extract and I extracted it with IPA getting a little more of freebase.
The puny amount, I think, but, as Albert Hoffman said (starting his work in Sandoz), we need to learn working with small amount of chemicals ;-)

Thank you for quick advice

masiukaalcohol draws water, better use dcm and use MgSO4 or Na2SO4 for dry solvent before distill

 

[Lordoftheshard 2]

I need help I did the reaction one a nice bath from the start the temp did not go above.5celcius only when one addition of nabr it took the temp to 40cekcius for 40secinds to then it went down to 3degrees further addition it never raised the temperature again as I made sure I didn't add as much as the the first addition when U dud do that first addition it had a real cats puss smell to I it after that the other addition no smell I followed everything ti the book I made something cause I had a layer in the DCM but when I went to proceed it with tartaric the l meth was stock to the tartrate buy the liquid which was suppose to have the g meth had nothing
Also with the P2P I did 20,brine washes to raise the oh which di nothing m to pH saturd at 2.5

 

[UWe9o12jkied91d]

I need help I did the reaction one a nice bath from the start the temp did not go above.5celcius only when one addition of nabr it took the temp to 40cekcius for 40secinds to then it went down to 3degrees further addition it never raised the temperature again as I made sure I didn't add as much as the the first addition when U dud do that first addition it had a real cats puss smell to I it after that the other addition no smell I followed everything ti the book I made something cause I had a layer in the DCM but when I went to proceed it with tartaric the l meth was stock to the tartrate buy the liquid which was suppose to have the g meth had nothing
Also with the P2P I did 20,brine washes to raise the oh which di nothing m to pH saturd at 2.5

Lordoftheshard 2depending on scale a nice bath might not be required from the very start, have it ready and use it as needed (if), but as long as your foaming is inside the flask let the reaction proceed without additional cooling
as far as your acidic p2p you could try bicarbonate sol. wash or steam distill your ketone

 

[Lordoftheshard 2]

I did both nothing changed the pH of the ketone I did external steam distillation if the way I do my meth now I found out the that you have to ad water to the flasks the fistill over how much water di I add to the flasks with within 100g of p2p

 

[rothschild33]

I reckon this is a 2 step reaction, imine formation then amine formation. Is there a good indication for imine formation, just to know that the reaction is working for troubleshooting purposes? And is there one for amine as well?

 

[UWe9o12jkied91d]

I reckon this is a 2 step reaction, imine formation then amine formation. Is there a good indication for imine formation, just to know that the reaction is working for troubleshooting purposes? And is there one for amine as well?

rothschild33TLC

 

[Lordoftheshard 2]

I did the internal steam distillation product changed from the orange brown colour to a nice yellow colour and pH has raised to pH 5 can I use this ad is or do I need to raise the pH to 7 as I want to do the reaction again to make product

 

[Lordoftheshard 2]

I did the internal steam distillation product changed from the orange brown colour to a nice yellow colour and pH has raised to pH 5 can I use this ad is or do I need to raise the pH to 7 as I want to do the reaction again to make product

Lordoftheshard 2Did the reaction all went well I worked out I got my ratios for the sodium borohydride wrong in the first attempt and fried the fuck out of things
This time cats piss FB also you don't have to use as much water as stated massive over kill I cut the water down buy a quarter and still . The product came out fine just doing a EU resolution now see how that works out btc thanks for your knowledge and sharing using pseudo to make meth or ppa to make 4 methylaminorex in my past this bmk p2p is a whole new world to me and your information that works I'm highly grateful for
All members if you need a source to acquire all the bmk Methylamine and sodium borohydride from 1kg to 1 ton 100% you will receive your product doesn't matter were you are in the world contact me

 

[Lordoftheshard 2]

Im.gking to be quiet honest and Frank here have any if you tried the product this makes strength wise iits fucken shit yrs you make a product but it does nothing not only me 4 other people said the same thing after producing product for the last 20 years I'm going to tell you all straight unless your reaction has a metal in it don't bother it's the metals that what give the product it's strength leg lithium bitch iodine hypophos/rp p2p aluminium amalgam your reaction has to be one of these else your just waisting time effort and money on producing shit
I'm not having a go at any one I'm just stating the facts thanks to btc bioss keep up the good work I'm going to try and find another method of yours that has metal in so I don't throw this p2p down the toilet all these methods without metal in them are to ifucken.us3l3ss

 

[Macondor]

Im.gking to be quiet honest and Frank here have any if you tried the product this makes strength wise iits fucken shit yrs you make a product but it does nothing not only me 4 other people said the same thing after producing product for the last 20 years I'm going to tell you all straight unless your reaction has a metal in it don't bother it's the metals that what give the product it's strength leg lithium bitch iodine hypophos/rp p2p aluminium amalgam your reaction has to be one of these else your just waisting time effort and money on producing shit
I'm not having a go at any one I'm just stating the facts thanks to btc bioss keep up the good work I'm going to try and find another method of yours that has metal in so I don't throw this p2p down the toilet all these methods without metal in them are to ifucken.us3l3ss

Lordoftheshard 2THIS IS THE SAME FOR mdma USING NaBH4? less potent? why the fuck?

 

[btcboss2022]

Im.gking to be quiet honest and Frank here have any if you tried the product this makes strength wise iits fucken shit yrs you make a product but it does nothing not only me 4 other people said the same thing after producing product for the last 20 years I'm going to tell you all straight unless your reaction has a metal in it don't bother it's the metals that what give the product it's strength leg lithium bitch iodine hypophos/rp p2p aluminium amalgam your reaction has to be one of these else your just waisting time effort and money on producing shit
I'm not having a go at any one I'm just stating the facts thanks to btc bioss keep up the good work I'm going to try and find another method of yours that has metal in so I don't throw this p2p down the toilet all these methods without metal in them are to ifucken.us3l3ss

Lordoftheshard 2Is impossible to discuss something when the main thing are "facts" based on personal feelings without any chemical or scientific argument.
Is very easy to understand pure MDMA is pure MDMA and pure D-Meth is pure D-meth if you obtain the pure product it's a unique compound with a unique molecule structure.

D-Meth

MDMA

If you have these pure and isolated molecules no matter the route you used with metal, without metal even with magical techniques...won't be any difference should be exactly the same.
About strength only could change about impurities(pure product concentration not enough isolated) or enantiomers separation(in that case won't be the exact molecule of the pic)
I can put in your hands 10 samples of pure product obtained with different routes and you never will know the route used on each, won't be distinguishable.

Easy example pure technical distilled H2O is pure H2O you won't know the technique used to get it you just have H2O.

With this I don't want to change your mind or your feelings when you use the product, I'm just explaining contrasted and real facts that could be shown to anybody anywhere with the same results.

Thanks.

 

[Lordoftheshard 2]

Is impossible to discuss something when the main thing are "facts" based on personal feelings without any chemical or scientific argument.
Is very easy to understand pure MDMA is pure MDMA and pure D-Meth is pure D-meth if you obtain the pure product it's a unique compound with a unique molecule structure.

D-Meth
View attachment 15328
MDMA
View attachment 15329
If you have these pure and isolated molecules no matter the route you used with metal, without metal even with magical techniques...won't be any difference should be exactly the same.
About strength only could change about impurities(pure product concentration not enough isolated) or enantiomers separation(in that case won't be the exact molecule of the pic)
I can put in your hands 10 samples of pure product obtained with different routes and you never will know the route used on each, won't be distinguishable.

Easy example pure technical distilled H2O is pure H2O you won't know the technique used to get it you just have H2O.

With this I don't want to change your mind or your feelings when you use the product, I'm just explaining contrasted and real facts that could be shown to anybody anywhere with the same results.

Thanks.

btcboss2022Thank you but as Hank said product made this way is weaker your always redosing
I
I've always made product from pseudo or ephedrine and it's always quality Im not putting anyone down and respect what you do for all of us with your synth and information
We did this synth 4tines to make sure there was no error and each time came up with the same result it makes a much weaker product not only me.5 people tested the product and said the same thing
Yes it makes a product no doubt about it as for strength and quality it wasn't there

 

[Lordoftheshard 2]

Thank you but as Hank said product made this way is weaker your always redosing
I
I've always made product from pseudo or ephedrine and it's always quality Im not putting anyone down and respect what you do for all of us with your synth and information
We did this synth 4tines to make sure there was no error and each time came up with the same result it makes a much weaker product not only me.5 people tested the product and said the same thing
Yes it makes a product no doubt about it as for strength and quality it wasn't there

Lordoftheshard 2If I sold that product in my country some one would shoot me its only good for cutters instead of using n -iso we already did tests.with meth made from pseudo and this product mixed and rexaled it's ,$700 cheaper a kilo than buying n-iso
I don't cut my product but I gave me.friend some of this product he mixed it with his pseudo product and recrystallized it

 

[w2x3f5]

Hello,

I checked leuckart route for Meth and later D-meth with tartaric and I can confirm that NaBH4 route has a particularity(I don't know what yet), this route give a Meth that is more difficult to isolate the D-Meth I don't know the reason but about this the "D-Meth" from NaBH4 route seems less effective.
Still don't have any sense for me but it's a fact checked myself.
I must try now cold way with methanol and methylamine but instead use NaBH4 as reducing agent I will use an aluminum amalgam and update you.
I hope this info helps.

btcboss2022I did meth on sodium borohydride, no problems arose when separating with d-tartaric acid in ethyl alcohol. The D-isomer crystallized, the L-isomer remained in the form of a thick oil after distillation of the alcohol. Unfortunately, I did not measure the angle of rotation.

 

[situ1984]

Thank you but as Hank said product made this way is weaker your always redosing
I
I've always made product from pseudo or ephedrine and it's always quality Im not putting anyone down and respect what you do for all of us with your synth and information
We did this synth 4tines to make sure there was no error and each time came up with the same result it makes a much weaker product not only me.5 people tested the product and said the same thing
Yes it makes a product no doubt about it as for strength and quality it wasn't there

Lordoftheshard 2Could you please tell me the steps of hydroiodic acid in ephedrine?

 

[Macondor]

Im.gking to be quiet honest and Frank here have any if you tried the product this makes strength wise iits fucken shit yrs you make a product but it does nothing not only me 4 other people said the same thing after producing product for the last 20 years I'm going to tell you all straight unless your reaction has a metal in it don't bother it's the metals that what give the product it's strength leg lithium bitch iodine hypophos/rp p2p aluminium amalgam your reaction has to be one of these else your just waisting time effort and money on producing shit
I'm not having a go at any one I'm just stating the facts thanks to btc bioss keep up the good work I'm going to try and find another method of yours that has metal in so I don't throw this p2p down the toilet all these methods without metal in them are to ifucken.us3l3ss

Lordoftheshard 2To the MDMA synth happen something similar?
Start from PMK glycidate and reduce with NaBH4 can make lees potent MDMA?
Start from piperonal and reduce with amalgam wil be better or start from PMK glycidate and reduce with amalgam?
please i want to make the best product for myself..i tired of buy shit for consume. yeasr ago..there was a really nice MD stuff...now is shitty shitty

 

[btcboss2022]

To the MDMA synth happen something similar?
Start from PMK glycidate and reduce with NaBH4 can make lees potent MDMA?
Start from piperonal and reduce with amalgam wil be better or start from PMK glycidate and reduce with amalgam?
please i want to make the best product for myself..i tired of buy shit for consume. yeasr ago..there was a really nice MD stuff...now is shitty shitty

MacondorStrangely with MDMA is totally the opposite, of all synth I did of MDMA the NaBH4 reduction give more potent product.
I can't explain why because I don't know exactly but I'm practically sure that all is about enantiomers resolution, in that case MDMA is totally racemic no resolution applied. Seems(not sure only based in experience) that NaBH4 is good to obtain good racemic products but not good route if later needs to make a resolution like meth for example.

 

[Woodshack]

Strangely with MDMA is totally the opposite, of all synth I did of MDMA the NaBH4 reduction give more potent product.
I can't explain why because I don't know exactly but I'm practically sure that all is about enantiomers resolution, in that case MDMA is totally racemic no resolution applied. Seems(not sure only based in experience) that NaBH4 is good to obtain good racemic products but not good route if later needs to make a resolution like meth for example.

btcboss2022Thank-you for your knowledge BTCBOSS! <3

 

[btcboss2022]

Im.gking to be quiet honest and Frank here have any if you tried the product this makes strength wise iits fucken shit yrs you make a product but it does nothing not only me 4 other people said the same thing after producing product for the last 20 years I'm going to tell you all straight unless your reaction has a metal in it don't bother it's the metals that what give the product it's strength leg lithium bitch iodine hypophos/rp p2p aluminium amalgam your reaction has to be one of these else your just waisting time effort and money on producing shit
I'm not having a go at any one I'm just stating the facts thanks to btc bioss keep up the good work I'm going to try and find another method of yours that has metal in so I don't throw this p2p down the toilet all these methods without metal in them are to ifucken.us3l3ss

Lordoftheshard 2You can do exactly the same process replacing NaBH4 by an aluminum amalgam as reductor but the rest the same.

 

[mithyl2]

what can be used instead of DCM?

 

[UWe9o12jkied91d]

what can be used instead of DCM?

mithyl2xylene, toluene, whitespirt, pether, diethyl ether, freon, propane, benzene, petrol from the pump, zippo lighter fluid get creative ni-

 

[mithyl2]

xylene, toluene, whitespirt, pether, diethyl ether, freon, propane, benzene, petrol from the pump, zippo lighter fluid get creative ni-

UWe9o12jkied91dis there a particular reason why DCM was given as the solvent to use? will i get a lesser yield if i use an alternative?

 

[UWe9o12jkied91d]

is there a particular reason why DCM was given as the solvent to use? will i get a lesser yield if i use an alternative?

mithyl2No, most likely not, DCM evaporates hella fast, it is why its preffered as an extraction solvent by some chemists.