4-MMC (mephedrone) synthesis. Complete video tutorial.

[Bazooka90]

I hear with NMP it is 15 min stirring and reaction come

rafael1985instead of nmp i use dmf so how much time for reaction to come?

 

[rafael1985]

You must have two layers reaction is finish

 

[rafael1985]

This I dont know why you dont do method with DCM or toluen with methylamine

 

[rafael1985]

What yield you have with 3 cmc

 

[Bazooka90]

First i put 400 toluene,100

This I dont know why you dont do method with DCM or toluen wi

rafael1985

This I dont know why you dont do method with DCM or toluen with methylamine

Hi,i did it like this
100 2br4m,500 toluene and 200 methylamine 40% stiring until it reaches 40 degrese after i add slowly 300dmf and stir again about 1hour .
For acidification i use55ml hcl 33%.
I don't know what i do wrong becouse my yield is around 15g after purification and crystalizati

 

[Bazooka90]

What yield you have with 3 cmc

rafael19853cmc yield is about 30grams but is very brownish

 

[VenomRCLab]

Temp toulen is 60°c no 40°c

 

[rafael1985]

A

3cmc yield is about 30grams but is very brownish

Bazooka90Did You clean this with acetone?

 

[VenomRCLab]

very low yield should be 70g to 80g 4mmc of pure crystal. With 2-bromo-4-methylpropiophenone

 

[KWasd]

I have a question from a different point of view. Suppose you have a completely airtight room, where fresh air is forced in on one side and a high-powered fan pulls it out of the centre of the room on the other.

How do you deal with the filtration of the odour in the air? Do you use any purifiers, if so, what kind and with what kind of cartridge, or is it enough to give a high-capacity carbon filter with activated carbon on the exhaust as is used in cannabis cultivation. If such a filter would do the job, which activated carbon is best, CTC or ordinary carbon?

How is the air and odours filtered in the laboratories? Regards

 

[Bazooka90]

A

Did You clean this with acetone

rafael1985

yes,i clean it several times

Temp toulen is 60°c no 40°c

 

[Bazooka90]

Temp toulen is 60°c no 40°c

VenomRCLabI didn't know that ,this is a good tip for me.so i must reach 60° not 40°.i must stay in 60°-80° range?

 

[rafael1985]

I didn't know that ,this is a good tip for me.so i must reach 60° not 40°.i must stay in 60°-80° range?

Bazooka90You have good ketone to make this.When You see two layers reaction is finish.You give 33-37% HCL or mix with water?

 

[Nnn]

3cmc yield is about 30grams but is very brownish

Bazooka90How much 2bromo 3 chloropropiophenone you will taken ,
And which solvent is used ,

 

[Bazooka90]

How much 2bromo 3 chloropropiophenone you will taken ,
And which solvent is used ,

NnnI use toluen mixed with 100 2br3cl and 200 methylamine 40% after reaching 40°(i am not sure is the right temperature)i put 300dmf drop by drop

 

[Bazooka90]

You have good ketone to make this.When You see two layers reaction is finish.You give 33-37% HCL or mix with water?

rafael1985i mix with water 3 times and after i put hcl 33%

 

[Bazooka90]

Can anybody tell the temperature for reaction in dmf?

 

[Nnn]

First i put 400 toluene,100



Hi,i did it like this
100 2br4m,500 toluene and 200 methylamine 40% stiring until it reaches 40 degrese after i add slowly 300dmf and stir again about 1hour .
For acidification i use55ml hcl 33%.
I don't know what i do wrong becouse my yield is around 15g after purification and crystalizati

Bazooka90

Can anybody tell the temperature for reaction in dmf?

Can anybody tell the temperature for reaction in dmf?

How much time will taken
You have to dissolve 2bromo 4methylpropiophenone in toulene

 

[Nnn]

I use toluen mixed with 100 2br3cl and 200 methylamine 40% after reaching 40°(i am not sure is the right temperature)i put 300dmf drop by drop

Bazooka90I think better is
Yu hav to replace toulene by NMP
AND
use benzene as extractor

 

[Bazooka90]

I think better is
Yu hav to replace toulene by NMP
AND
use benzene as extractor

Nnnreplace dmf with benzen?