Synthesis of Amphetamines (Phenylethylamines)

Synthesis of amphetamines (phenylethylamines)
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G.Patton
Date added
Jul 5, 2023
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115
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ephedrine tablets ice methamphetamine
1) BMK ethyl glycidate synthesis from benzaldehyde.
2) BMK glycidic acid (sodium salt) synthesis BMK ethyl glycidate.
3) Phenylacetone (P2P) synthesis from BMK glycidic acid (sodium salt).

https://bbgate.com/threads/phenylacetone-p2p-synthesis-via-bmk-ethyl-glycidate.7549/
A 2,5-Dimethoxybenzaldehyde and nitroethane condensation produces 1-(2,5-dimethoxyphenyl)-2-nitropropene. A 1-(2,5-Dimethoxyphenyl)-2-nitropropene reduction gives 2,5-dimethoxyamphetamine (2,5-DMA) free base.

https://bbgate.com/threads/dox-phenethylamines-series-dob-dom-doi-doc-syntheses.1697/
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